Retention of duplicated genes in evolution

E Kuzmin, JS Taylor, C Boone - Trends in Genetics, 2022 - cell.com
Gene duplication is a prevalent phenomenon across the tree of life. The processes that lead
to the retention of duplicated genes are not well understood. Functional genomics …

Maintenance of duplicate genes and their functional redundancy by reduced expression

W Qian, BY Liao, AYF Chang, J Zhang - Trends in Genetics, 2010 - cell.com
Although evolutionary theories predict functional divergence between duplicate genes,
many old duplicates still maintain a high degree of functional similarity and are synthetically …

Mechanistic links between cellular trade-offs, gene expression, and growth

AY Weiße, DA Oyarzún, V Danos… - Proceedings of the …, 2015 - National Acad Sciences
Intracellular processes rarely work in isolation but continually interact with the rest of the cell.
In microbes, for example, we now know that gene expression across the whole genome …

Evolutionary convergence of pathway-specific enzyme expression stoichiometry

JB Lalanne, JC Taggart, MS Guo, L Herzel, A Schieler… - Cell, 2018 - cell.com
Coexpression of proteins in response to pathway-inducing signals is the founding paradigm
of gene regulation. However, it remains unexplored whether the relative abundance of co …

Exploring whole-genome duplicate gene retention with complex genetic interaction analysis

E Kuzmin, B VanderSluis, AN Nguyen Ba, W Wang… - Science, 2020 - science.org
INTRODUCTION Whole-genome duplication (WGD) events are pervasive in eukaryotes,
sha** the genomes of simple single-celled organisms, such as yeast, as well as those of …

Genome and gene duplications and gene expression divergence: a view from plants

Y Wang, X Wang, AH Paterson - … of the New York Academy of …, 2012 - Wiley Online Library
With many plant genomes sequenced, it is now clear that one distinguishing feature of
angiosperm (flowering plant) genomes is their high frequency of whole‐genome duplication …

Dynamic evolution of small signalling peptide compensation in plant stem cell control

CT Kwon, L Tang, X Wang, I Gentile, A Hendelman… - Nature Plants, 2022 - nature.com
Gene duplications are a hallmark of plant genome evolution and a foundation for genetic
interactions that shape phenotypic diversity,,,–. Compensation is a major form of paralogue …

Predicting mutation outcome from early stochastic variation in genetic interaction partners

A Burga, MO Casanueva, B Lehner - Nature, 2011 - nature.com
Many mutations, including those that cause disease, only have a detrimental effect in a
subset of individuals. The reasons for this are usually unknown, but may include additional …

Adaptive response and tolerance to sugar and salt stress in the food yeast Zygosaccharomyces rouxii

TC Dakal, L Solieri, P Giudici - International Journal of Food Microbiology, 2014 - Elsevier
The osmotolerant and halotolerant food yeast Zygosaccharomyces rouxii is known for its
ability to grow and survive in the face of stress caused by high concentrations of non-ionic …

Gene duplication can impart fragility, not robustness, in the yeast protein interaction network

G Diss, I Gagnon-Arsenault, AM Dion-Coté, H Vignaud… - Science, 2017 - science.org
The maintenance of duplicated genes is thought to protect cells from genetic perturbations,
but the molecular basis of this robustness is largely unknown. By measuring the interaction …