NIA‐AA research framework: toward a biological definition of Alzheimer's disease

CR Jack Jr, DA Bennett, K Blennow… - Alzheimer's & …, 2018 - Wiley Online Library
Abstract In 2011, the National Institute on Aging and Alzheimer's Association created
separate diagnostic recommendations for the preclinical, mild cognitive impairment, and …

Inflammation and Alzheimer's disease

H Akiyama, S Barger, S Barnum, B Bradt, J Bauer… - Neurobiology of …, 2000 - Elsevier
Inflammation clearly occurs in pathologically vulnerable regions of the Alzheimer's disease
(AD) brain, and it does so with the full complexity of local peripheral inflammatory responses …

Alzheimer's disease

K Blennow, MJ de Leon, H Zetterberg - The Lancet, 2006 - thelancet.com
Alzheimer's disease is the most common cause of dementia. Research advances have
enabled detailed understanding of the molecular pathogenesis of the hallmarks of the …

Neurocognitive deficit in schizophrenia: a quantitative review of the evidence.

RW Heinrichs, KK Zakzanis - Neuropsychology, 1998 - psycnet.apa.org
The neurocognitive literature on test performance in schizophrenia is reviewed
quantitatively. The authors report 22 mean effect sizes from 204 studies to index …

Atrophy of medial temporal lobes on MRI in" probable" Alzheimer's disease and normal ageing: diagnostic value and neuropsychological correlates.

P Scheltens, D Leys, F Barkhof, D Huglo… - Journal of Neurology …, 1992 - jnnp.bmj.com
Magnetic resonance imaging (MRI) has shown a great reduction in medial temporal lobe
and hippocampal volume of patients with Alzheimer's disease as compared to controls …

Impact of multiple pathologies on the threshold for clinically overt dementia

A Kapasi, C DeCarli, JA Schneider - Acta neuropathologica, 2017 - Springer
Longitudinal clinical–pathological studies have increasingly recognized the importance of
mixed pathologies (the coexistence of one or more neurodegenerative and cerebrovascular …

The lifespan human connectome project in aging: an overview

SY Bookheimer, DH Salat, M Terpstra, BM Ances… - Neuroimage, 2019 - Elsevier
Abstract The original Human Connectome Project yielded a rich data set on structural and
functional connectivity in a large sample of healthy young adults using improved methods of …

MR‐based hippocampal volumetry in the diagnosis of Alzheimer's disease

CR Jack Jr, RC Petersen, PC O'brien, EG Tangalos - Neurology, 1992 - AAN Enterprises
We evaluated a new magnetic resonance (MR)-based technique for performing volumetric
measurements of temporal lobe structures. The technique was designed to assist in making …

Measurement of radiotracer concentration in brain gray matter using positron emission tomography: MRI-based correction for partial volume effects

HW Müller-Gärtner, JM Links… - Journal of Cerebral …, 1992 - journals.sagepub.com
Accuracy in in vivo quantitation of brain function with positron emission tomography (PET)
has often been limited by partial volume effects. This limitation becomes prominent in …

Patterns of temporal lobe atrophy in semantic dementia and Alzheimer's disease

D Chan, NC Fox, RI Scahill, WR Crum… - Annals of …, 2001 - Wiley Online Library
Volumetric magnetic resonance imaging analyses of 30 subjects were undertaken to
quantify the global and temporal lobe atrophy in semantic dementia and Alzheimer's …