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Brain insulin resistance: role in neurodegenerative disease and potential for targeting
C Hölscher - Expert opinion on investigational drugs, 2020 - Taylor & Francis
Introduction: This review evaluates the novel strategy of treating Alzheimer's and Parkinson's
disease (AD and PD) withdrugs that initially have been developed to treat type 2 diabetes …
disease (AD and PD) withdrugs that initially have been developed to treat type 2 diabetes …
NF‐κB/NLRP3 inflammasome axis and risk of Parkinson's disease in type 2 diabetes mellitus: a narrative review and new perspective
Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's disease (AD). Genetic predisposition and immune dysfunction are involved in …
Alzheimer's disease (AD). Genetic predisposition and immune dysfunction are involved in …
[HTML][HTML] Promising use of metformin in treating neurological disorders: biomarker-guided therapies
A Loan, C Syal, M Lui, L He, J Wang - Neural Regeneration …, 2024 - journals.lww.com
Neurological disorders are a diverse group of conditions that affect the nervous system and
include neurodegenerative diseases (Alzheimer's disease, multiple sclerosis, Parkinson's …
include neurodegenerative diseases (Alzheimer's disease, multiple sclerosis, Parkinson's …
Toxic interactions between dopamine, α-synuclein, monoamine oxidase, and genes in mitochondria of Parkinson's disease
M Naoi, W Maruyama, M Shamoto-Nagai… - Journal of Neural …, 2024 - Springer
Parkinson's disease is characterized by its distinct pathological features; loss of dopamine
neurons in the substantia nigra pars compacta and accumulation of Lewy bodies and Lewy …
neurons in the substantia nigra pars compacta and accumulation of Lewy bodies and Lewy …
Challenges of repurposing tetracyclines for the treatment of Alzheimer's and Parkinson's disease
I Markulin, M Matasin, VE Turk… - Journal of neural …, 2022 - Springer
The novel antibiotic-exploiting strategy in the treatment of Alzheimer's (AD) and Parkinson's
(PD) disease has emerged as a potential breakthrough in the field. The research in animal …
(PD) disease has emerged as a potential breakthrough in the field. The research in animal …
Modeling of Parkinson's disease by intrastriatal administration of streptozotocin
Parkinson's disease (PD) is a highly heterogeneous and therefore a possible cause of
translation failure of drugs from animal testing to human treatments can be because existing …
translation failure of drugs from animal testing to human treatments can be because existing …
Persistence and severity of cutaneous manifestations in IgA vasculitis is associated with development of IgA vasculitis nephritis in children
Abstract Background/Objective: The purpose of this study was to evaluate the prevalence
and severity of skin involvement in children with IgA vasculitis (IgAV) and its relationship with …
and severity of skin involvement in children with IgA vasculitis (IgAV) and its relationship with …
Disbalance of the duodenal epithelial cell turnover and apoptosis accompanies insensitivity of intestinal redox homeostasis to inhibition of the brain glucose …
Introduction: Gastrointestinal dyshomeostasis is investigated in the context of metabolic
dysfunction, systemic, and neuroinflammation in Alzheimer's disease. Dysfunctional …
dysfunction, systemic, and neuroinflammation in Alzheimer's disease. Dysfunctional …
Additional methodological considerations regarding optimization of the dose of intracerebroventricular streptozotocin A response to:“Optimization of …
A recent article by Ghosh et al. entitled" Optimization of intracerebroventricular
streptozotocin dose for the induction of neuroinflammation and memory impairments in rats" …
streptozotocin dose for the induction of neuroinflammation and memory impairments in rats" …
Association of cognitive deficit with glutamate and insulin signaling in a rat model of Parkinson's disease
Cognitive deficit is a frequent non-motor symptom in Parkinson's disease (PD) with an
unclear pathogenesis. Recent research indicates possible involvement of insulin resistance …
unclear pathogenesis. Recent research indicates possible involvement of insulin resistance …