Experimental and CFD physical characterization of animal cell bioreactors: from micro-to production scale
Transfer of mammalian cell culture processes across stirred and aerated bioreactor scales is
a delicate task, frequently leading to different conditions across scales. To provide a more …
a delicate task, frequently leading to different conditions across scales. To provide a more …
Experimental and modeling study of breakage and restructuring of open and dense colloidal aggregates
In this work we present experimental and simulation analysis of the breakage and
restructuring of colloidal aggregates in dilute conditions under shear. In order to cover a …
restructuring of colloidal aggregates in dilute conditions under shear. In order to cover a …
Determination of the maximum operating range of hydrodynamic stress in mammalian cell culture
B Neunstoecklin, M Stettler, T Solacroup, H Broly… - Journal of …, 2015 - Elsevier
Application of quality by design (QbD) requires identification of the maximum operating
range for parameters affecting the cell culture process. These include hydrodynamic stress …
range for parameters affecting the cell culture process. These include hydrodynamic stress …
Shear-induced breakup of cellulose nanocrystal aggregates
HN Xu, YY Tang, XK Ouyang - Langmuir, 2017 - ACS Publications
The flow properties of two kinds of cellulose nanocrystal (CNC) rods with different aspect
ratios and similar zeta potentials in aqueous suspensions have been investigated. The …
ratios and similar zeta potentials in aqueous suspensions have been investigated. The …
Response of shear‐activated nanotherapeutic particles in a clot‐obstructed blood vessel by CFD‐DEM simulations
In recent years, targeted drug delivery systems have been regarded as a promising solution
to enhance the efficiency of treatments against clots in blood vessels. In this context, shear …
to enhance the efficiency of treatments against clots in blood vessels. In this context, shear …
Breakage rate of colloidal aggregates in shear flow through Stokesian dynamics
We study the first breakage event of colloidal aggregates exposed to shear flow by detailed
numerical analysis of the process. We have formulated a model, which uses Stokesian …
numerical analysis of the process. We have formulated a model, which uses Stokesian …
Temperature influence on MBS latex aggregate morphology
A Hamieh, C Coufort-Saudejaud, A Couffin… - Colloids and Surfaces A …, 2023 - Elsevier
This paper aims to better understand the impact of process conditions on the morphological
properties of MBS (Methacrylate Butadiene Styrene) core-shell latex aggregates during an …
properties of MBS (Methacrylate Butadiene Styrene) core-shell latex aggregates during an …
Generation and geometrical analysis of dense clusters with variable fractal dimension
The generation and geometrical analysis of clusters composed of rigid monodisperse
primary particles with variable fractal dimension, df, in the range from 2.2 to 3 are presented …
primary particles with variable fractal dimension, df, in the range from 2.2 to 3 are presented …
Revealing Crystal Aggregates' Evolution through In Situ Visualization in Cooling Crystallization
The transition process and control mechanisms of crystal aggregates to agglomerates hold
significant importance in reducing subsequent processing steps and enhancing crystal …
significant importance in reducing subsequent processing steps and enhancing crystal …
Texture, transport and mechanical properties of graphite nanoplatelet/silicone composites produced by three roll mill
Thermally conducting and highly compliant composites for thermal interface applications
were developed by dispersing graphite nanoplatelets (GNPs) in silicone polymer using a …
were developed by dispersing graphite nanoplatelets (GNPs) in silicone polymer using a …