Bis‐heterocycles (BHCs) are hybrid molecules comprising two linked, bound, spacer, or
fused heterocyclic skeletons. In recent years, these compounds have attracted increased …

The review covers the results of studies published in the literature on the synthesis of spiro‐
linked heterocycles of the indole, quinoline, benzoxazine, benzothiazine …

Lactams are very important heterocycles as a result of their presence in a wide range of
bioactive molecules, natural products and drugs, and also due their utility as versatile …

A new synthetic strategy to obtain new linked 1, 5-disubstituted tetrazole-1, 2, 3-triazoles via
the Ugi-azide reaction followed by a copper-catalyzed alkyne-azide reaction (CuAAC) was …

6-Triazolylmethyl-pyrrolo [3, 4-b] pyridin-5-one tris-heterocycles were synthesized in 43–
57% overall yields. The two-stage synthesis involved a cascade process (Ugi-3CR/aza Diels …

Ugi-azide four-component reaction (UA-4CR) as development on Ugi four-component
reaction (U-4CR) is the condensation reaction involving an aldehyde, an amine, an …

An efficient sequence based on the Ugi-azide reaction and rhodium (III)-catalyzed
intermolecular annulation has been established for the preparation of tetrazole …

A novel strategy via the triple process (multicomponent reactions (MCR)-domino)/tandem
was developed for the synthesis of restricted and constrained bis-1, 2, 3-triazole-linked …

The Ugi-azide MCR (UA) is one of the most efficient methods for the synthesis of 1, 5-
disubstituted-1H-tetrazoles (1, 5-DS-T). Complex drug-like scaffolds incorporating tetrazoles …

A straight forward and highly efficient one-pot annulation of 2-aminobenzothiazole,(E)-N-
methyl-1-(methylthio)-2-nitroethenamine, and aldehydes in the presence of FeF 3 is …