Ketogenesis and ketolysis are central metabolic processes activated during the response to
fasting. Ketogenesis is regulated in multiple stages, and a nuclear receptor peroxisome …

Epilepsy often develops in patients with glioma, and the two conditions share common
pathogenic mechanisms. Altered expression of glutamate transporters, including the cystine …

Signalling lipids are known to control a wide array of cellular processes, including cell
proliferation, apoptosis, migration, and energy metabolism. Fatty acids and their derivatives …

Fatty acids play a crucial role in the brain as specific receptor ligands and as precursors of
bioactive metabolites. Conjugated linoleic acid (CLA), a group of positional and geometric …

The peroxisome proliferator-activated receptor gamma (PPARγ), which belongs to the family
of nuclear receptors, has been mainly studied as an important factor in metabolic disorders …

Peroxisome proliferator‐activated receptors (PPAR s) are ligand‐activated transcription
factors that modulate the expression of multiple different genes involved in the regulation of …

Capric acid (CA10) is a 10-carbon medium-chain fatty acid abundant in the medium-chain
triglyceride ketogenic diet (MCT KD). The purpose of this study was to characterize acute …

Alzheimer's disease (AD) is the leading cause of dementia in the elderly. Mutations in genes
encoding proteins involved in amyloid-β peptide (Aβ) production are responsible for …

Background The social motivational theory of autism spectrum disorder (ASD) focuses on
social anhedonia as key causal feature of the impaired peer relationships that characterize …

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that act
as ligand-activated transcription factors. Although prescribed for dyslipidemia and type-II …