RNAi-based therapeutics and tumor targeted delivery in cancer
Over the past decade, non-coding RNA-based therapeutics have proven as a great potential
for the development of targeted therapies for cancer and other diseases. The discovery of …
for the development of targeted therapies for cancer and other diseases. The discovery of …
Polymeric micelles and cancer therapy: An ingenious multimodal tumor-targeted drug delivery system
Since the beginning of pharmaceutical research, drug delivery methods have been an
integral part of it. Polymeric micelles (PMs) have emerged as multifunctional nanoparticles in …
integral part of it. Polymeric micelles (PMs) have emerged as multifunctional nanoparticles in …
Polymeric nanocarriers of drug delivery systems in cancer therapy
N Avramović, B Mandić, A Savić-Radojević, T Simić - Pharmaceutics, 2020 - mdpi.com
Conventional chemotherapy is the most common therapeutic method for treating cancer by
the application of small toxic molecules thatinteract with DNA and causecell death …
the application of small toxic molecules thatinteract with DNA and causecell death …
Recent advances in develo** polymeric micelles for treating cancer: Breakthroughs and bottlenecks in their clinical translation
Polymeric micelles (PMs) have been explored pre-clinically for the delivery of
chemotherapeutics to treat cancer. Their unique features, such as easy surface …
chemotherapeutics to treat cancer. Their unique features, such as easy surface …
Recent advances of metal-based nanoparticles in nucleic acid delivery for therapeutic applications
AR Sharma, YH Lee, A Bat-Ulzii… - Journal of …, 2022 - Springer
Recent efforts in designing nanomaterials to deliver potential therapeutics to the targeted
site are overwhelming and palpable. Engineering nanomaterials to deliver biological …
site are overwhelming and palpable. Engineering nanomaterials to deliver biological …
Fundamentals of siRNA and miRNA therapeutics and a review of targeted nanoparticle delivery systems in breast cancer
Gene silencing via RNA interference (RNAi) is rapidly evolving as a personalized approach
to cancer treatment. The effector molecules—small interfering RNAs (siRNAs) and …
to cancer treatment. The effector molecules—small interfering RNAs (siRNAs) and …
Efficient nanocarriers of siRNA therapeutics for cancer treatment
Nanocarriers as drug delivery systems are promising and becoming popular, especially for
cancer treatment. In addition to improving the pharmacokinetics of poorly soluble …
cancer treatment. In addition to improving the pharmacokinetics of poorly soluble …
siRNA based drug design, quality, delivery and clinical translation
Gene silencing by RNA interference represents a promising therapeutic approach. The
development of carriers, eg, polymers, lipids, peptides, antibodies, aptamers, small …
development of carriers, eg, polymers, lipids, peptides, antibodies, aptamers, small …
Biodegradable polymers for gene delivery
TJ Thomas, HA Tajmir-Riahi, CKS Pillai - Molecules, 2019 - mdpi.com
The cellular transport process of DNA is hampered by cell membrane barriers, and hence, a
delivery vehicle is essential for realizing the potential benefits of gene therapy to combat a …
delivery vehicle is essential for realizing the potential benefits of gene therapy to combat a …
Delivery systems for nucleic acids and proteins: Barriers, cell capture pathways and nanocarriers
Gene therapy has been used as a potential approach to address the diagnosis and
treatment of genetic diseases and inherited disorders. In this line, non-viral systems have …
treatment of genetic diseases and inherited disorders. In this line, non-viral systems have …