Cytogenetics in acute leukemia
Cytogenetic analyses in acute myeloid leukemia (AML) and acute lymphoblastic leukemia
(ALL) have revealed a great number of non-random chromosome abnormalities. In many …
(ALL) have revealed a great number of non-random chromosome abnormalities. In many …
Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research …
Pretreatment cytogenetics is a known predictor of outcome in hematologic malignancies.
However, its usefulness in adult acute lymphoblastic leukemia (ALL) is generally limited to …
However, its usefulness in adult acute lymphoblastic leukemia (ALL) is generally limited to …
T-cell lymphoblastic lymphoma and leukemia: different diseases from a common premalignant progenitor?
E Kroeze, JLC Loeffen, VM Poort… - Blood …, 2020 - ashpublications.org
T-cell lymphoblastic lymphoma (T-LBL) and lymphoblastic leukemia (T-ALL) represent
malignancies that arise from the transformation of immature precursor T cells. Similarities in …
malignancies that arise from the transformation of immature precursor T cells. Similarities in …
A comprehensive genetic classification of adult acute lymphoblastic leukemia (ALL): analysis of the GIMEMA 0496 protocol
M Mancini, D Scappaticci, G Cimino, M Nanni, V Derme… - Blood, 2005 - ashpublications.org
Abstract The Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) 0496 protocol,
through the central handling of bone marrow samples at presentation, allowed us to …
through the central handling of bone marrow samples at presentation, allowed us to …
Gene expression profiles of B-lineage adult acute lymphocytic leukemia reveal genetic patterns that identify lineage derivation and distinct mechanisms of …
Purpose: To characterize gene expression signatures in acute lymphocytic leukemia (ALL)
cells associated with known genotypic abnormalities in adult patients. Experimental Design …
cells associated with known genotypic abnormalities in adult patients. Experimental Design …
Adult acute lymphoblastic leukaemia
R Bassan, G Gatta, C Tondini, R Willemze - Critical reviews in oncology …, 2004 - Elsevier
Acute lymphoblastic leukaemia (ALL) in adults is a relatively rare neoplasm with a curability
rate around 30% at 5 years. This consideration makes it imperative to dissect further the …
rate around 30% at 5 years. This consideration makes it imperative to dissect further the …
Adult T-cell acute lymphoblastic leukemia: biologic profile at presentation and correlation with response to induction treatment in patients enrolled in the GIMEMA LAL …
Abstract Between 1996 and 2000, 90 newly diagnosed adult patients with T-acute
lymphoblastic leukemia (T-ALL) were registered in the G ruppo I taliano M alattie Ema …
lymphoblastic leukemia (T-ALL) were registered in the G ruppo I taliano M alattie Ema …
[HTML][HTML] Gene polymorphisms in folate metabolizing enzymes in adult acute lymphoblastic leukemia: effects on methotrexate-related toxicity and survival
Background The antifolate agent methotrexate is an important component of maintenance
therapy in acute lymphoblastic leukemia, although methotrexate-related toxicity is often a …
therapy in acute lymphoblastic leukemia, although methotrexate-related toxicity is often a …
Current status and future directions of T‐lymphoblastic lymphoma in children and adolescents
B Burkhardt, S Mueller, T Khanam… - British journal of …, 2016 - Wiley Online Library
The main challenges in the treatment of T‐cell lymphoblastic lymphoma (T‐LBL) in children
and adolescents are twofold: to increase survival rates in concert with reduction of acute and …
and adolescents are twofold: to increase survival rates in concert with reduction of acute and …
Abnormal methylation of the common PARK2 and PACRG promoter is associated with downregulation of gene expression in acute lymphoblastic leukemia and …
X Agirre, J Román‐Gómez, I Vázquez… - … journal of cancer, 2006 - Wiley Online Library
The PARK2 gene, previously identified as a mutated target in patients with autosomal
recessive juvenile parkinsonism (ARJP), has recently been found to be a candidate tumor …
recessive juvenile parkinsonism (ARJP), has recently been found to be a candidate tumor …