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Targeting breast cancer stem cells
The potential roles of breast cancer stem cells (BCSCs) in tumor initiation and recurrence
have been recognized for many decades. Due to their strong capacity for self-renewal and …
have been recognized for many decades. Due to their strong capacity for self-renewal and …
The role of CD36 in cancer progression and its value as a therapeutic target
Cluster of differentiation 36 (CD36) is a cell surface scavenger receptor that plays critical
roles in many different types of cancer, notably breast, brain, and ovarian cancers. While it is …
roles in many different types of cancer, notably breast, brain, and ovarian cancers. While it is …
[HTML][HTML] Golgi complex: a signaling hub in cancer
The Golgi Complex is the central hub in the endomembrane system and serves not only as a
biosynthetic and processing center but also as a trafficking and sorting station for …
biosynthetic and processing center but also as a trafficking and sorting station for …
[HTML][HTML] Breast cancer stem cells: Signaling pathways, cellular interactions, and therapeutic implications
Simple Summary Cancer stem cells (CSCs) in breast cancer have been identified for almost
two decades. Many outstanding discoveries have established the important functions of …
two decades. Many outstanding discoveries have established the important functions of …
The Emerging Role of LPA as an Oncometabolite
Lysophosphatidic acid (LPA) is a phospholipid that displays potent signalling activities that
are regulated in both an autocrine and paracrine manner. It can be found both extra-and …
are regulated in both an autocrine and paracrine manner. It can be found both extra-and …
Cancer stem cells from definition to detection and targeted drugs
B Ruszkowska-Ciastek, K Kwiatkowska… - International Journal of …, 2024 - mdpi.com
Cancers remain the second leading cause of mortality in the world. Preclinical and clinical
studies point an important role of cancer/leukaemia stem cells (CSCs/LSCs) in the …
studies point an important role of cancer/leukaemia stem cells (CSCs/LSCs) in the …
Endothelial cell–leukemia interactions remodel drug responses, uncovering T-ALL vulnerabilities
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive and often incurable disease.
To uncover therapeutic vulnerabilities, we first developed T-ALL patient–derived tumor …
To uncover therapeutic vulnerabilities, we first developed T-ALL patient–derived tumor …
[HTML][HTML] The multifaceted mechanisms of Dihydrotanshinone I in the treatment of tumors
J Yue, D Hao, Y Wang, J Guo, S Liu, L Meng… - Biomedicine & …, 2024 - Elsevier
The morbidity and mortality of malignant tumors are progressively rising on an annual basis.
Traditional Chinese Medicine (TCM) holds promise as a possible therapeutic agent for the …
Traditional Chinese Medicine (TCM) holds promise as a possible therapeutic agent for the …
[HTML][HTML] Protein kinase D1 signaling in cancer stem cells with epithelial-mesenchymal plasticity
Pancreatic neuroendocrine tumors (pNETs) are extremely diverse and highly vascularized
neoplasms that arise from endocrine cells in the pancreas. The pNETs harbor a …
neoplasms that arise from endocrine cells in the pancreas. The pNETs harbor a …
Anticancer Activity of Sargassum fluitans Extracts in Different Cancer Cells
> Background: The arrival of large quantities of Sargassum in the Mexican Caribbean Sea
has generated major environmental, health and economic problems. Although Sargassum …
has generated major environmental, health and economic problems. Although Sargassum …