Motivation In contrast to messenger RNAs, the function of the wide range of existing long
noncoding RNAs (lncRNAs) largely depends on their structure, which determines …

An RNA structure prediction from a single‐sequence RNA folding program is not evidence
for an RNA whose structure is important for function. Random sequences have plausible …

Background Aberrant mitochondrial fission, a critical pathological event underlying
myocardial ischemia/reperfusion (MI/R) injury, has emerged as a potential therapeutic …

Covariation induced by compensatory base substitutions in RNA alignments is a great way
to deduce conserved RNA structure, in principle. In practice, success depends on many …

Long noncoding RNAs (lncRNAs) have emerged as prominent regulators of gene
expression in eukaryotes. The identification of lncRNA orthologs is essential in efforts to …

Long noncoding RNAs (lncRNAs) are products of pervasive transcription that closely
resemble messenger RNAs on the molecular level, yet function through largely unknown …

Binding of microRNAs (miRNAs) to mRNAs normally results in post-transcriptional
repression of gene expression. However, extensive base-pairing between miRNAs and …

Long non‐coding (lnc) RNAs have been implicated in a plethora of normal biological
functions, and have also emerged as key molecules in various disease processes. OIP5 …

Long ncRNAs (lncRNAs) have been shown to play a biological and physiological role in
various tissues including the heart. We and others have previously established that the …

Many biologically important RNAs fold into specific 3D structures conserved through
evolution. Knowing when an RNA sequence includes a conserved RNA structure that could …