Hypertension in HIV-infected adults: novel pathophysiologic mechanisms

SA Fahme, GS Bloomfield, R Peck - Hypertension, 2018 - Am Heart Assoc
Fahme et al Mechanisms of Hypertension in HIV 45 have been shown to be associated with
hypertension in the context of HIV infection. 23, 34 In a nested, case–control study of HIV …

Inflammation, immune activation, and cardiovascular disease in HIV

E Nou, J Lo, SK Grinspoon - Aids, 2016 - journals.lww.com
Cardiovascular disease is one of the leading causes of morbidity and mortality in people
living with HIV. Several epidemiological studies have shown an increased risk of myocardial …

CD4/CD8 ratio normalisation and non-AIDS-related events in individuals with HIV who achieve viral load suppression with antiretroviral therapy: an observational …

C Mussini, P Lorenzini, A Cozzi-Lepri, G Lapadula… - The lancet HIV, 2015 - thelancet.com
Background In patients with HIV, immune reconstitution after antiretroviral therapy (ART) is
often incomplete. We assessed the probability of patients reaching a CD4/CD8 ratio of 1 or …

Herpesviruses: harmonious pathogens but relevant cofactors in other diseases?

S Sehrawat, D Kumar, BT Rouse - Frontiers in cellular and infection …, 2018 - frontiersin.org
Most vertebrates are infected with one or more herpesviruses and remain so for the rest of
their lives. The relationship of immunocompetent healthy host with herpesviruses may …

Tissue reservoirs of antiviral T cell immunity in persistent human CMV infection

CL Gordon, M Miron, JJC Thome, N Matsuoka… - Journal of Experimental …, 2017 - rupress.org
T cell responses to viruses are initiated and maintained in tissue sites; however, knowledge
of human antiviral T cells is largely derived from blood. Cytomegalovirus (CMV) persists in …

Ongoing burden of disease and mortality from HIV/CMV coinfection in Africa in the antiretroviral therapy era

E Adland, P Klenerman, P Goulder… - Frontiers in …, 2015 - frontiersin.org
Human Cytomegalovirus (CMV) is a well-recognized pathogen in the context of HIV
infection, but since the roll out of ART, clinical and scientific interest in the problem of …

[HTML][HTML] A viral exposure signature defines early onset of hepatocellular carcinoma

J Liu, W Tang, A Budhu, M Forgues, MO Hernandez… - Cell, 2020 - cell.com
Hepatocellular carcinoma (HCC) is an aggressive malignancy with its global incidence and
mortality rate continuing to rise, although early detection and surveillance are suboptimal …

HIV infection and immune activation: the role of coinfections

A Boulougoura, I Sereti - Current Opinion in HIV and AIDS, 2016 - journals.lww.com
Better understanding of the role of opportunistic infections at ART initiation and IRIS
pathogenesis will assist in improved strategies for prevention and treatment. The long-term …

Partners in crime: the role of CMV in immune dysregulation and clinical outcome during HIV infection

ML Freeman, MM Lederman, S Gianella - Current HIV/AIDS Reports, 2016 - Springer
In the current era of combination antiretroviral therapy (ART), human immunodeficiency virus
(HIV)-infected individuals are living longer and healthier lives. Nevertheless, HIV-infected …

Systemic inflammation associated with immune reconstitution inflammatory syndrome in persons living with HIV

CL Vinhaes, M Araujo-Pereira, R Tibúrcio… - Life, 2021 - mdpi.com
Antiretroviral therapy (ART) has represented a major advancement in the care of people
living with HIV (PLWHH), resulting in significant reductions in morbidity and mortality through …