High-density lipoprotein (HDL) has been proposed to have several antiatherosclerotic
properties, including the ability to mediate macrophage cholesterol efflux, antioxidant …

At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

ABCA1, an ATP-binding cassette (ABC) subfamily A exporter, mediates the cellular efflux of
phospholipids and cholesterol to the extracellular acceptor apolipoprotein AI (apoA-I) for …

Strong experimental evidence confirms that HDL directly alleviates atherosclerosis. HDL
particles display diverse atheroprotective functions in reverse cholesterol transport (RCT) …

Curcumin, a bioactive polyphenol, is a yellow pigment of the Curcuma longa (turmeric) plant.
Curcumin has many pharmacologic effects including antioxidant, anti-carcinogenic, anti …

Objective—Diminished cholesterol efflux activity of apolipoprotein B (apoB)–depleted serum
is associated with prevalent coronary artery disease, but its prognostic value for incident …

High-density lipoprotein heterogeneity and function in rever... : Current Opinion in Lipidology
High-density lipoprotein heterogeneity and function in reverse cholesterol transport : Current …

Cellular membranes are not homogenous mixtures of proteins; rather, they are segregated
into microdomains on the basis of preferential association between specific lipids and …

The maintenance of cellular cholesterol homeostasis is essential for normal cell function and
viability. Excessive cholesterol accumulation is detrimental to cells and serves as the …

ABCA1 functions as a lipid transporter because it mediates the transfer of cellular
phospholipid (PL) and free (unesterified) cholesterol (FC) to apoA-I and related proteins …