Pathogenesis of triple-negative breast cancer

F Derakhshan, JS Reis-Filho - Annual Review of Pathology …, 2022‏ - annualreviews.org
Triple-negative breast cancer (TNBC) encompasses a heterogeneous group of
fundamentally different diseases with different histologic, genomic, and immunologic …

[HTML][HTML] Pyroptosis: a new frontier in cancer

Y Fang, S Tian, Y Pan, W Li, Q Wang, Y Tang… - Biomedicine & …, 2020‏ - Elsevier
Pyroptosis is an inflammatory form of cell death triggered by certain inflammasomes, leading
to the cleavage of gasdermin D (GSDMD) and activation of inactive cytokines like IL-18 and …

Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin

EM Grasset, M Dunworth, G Sharma, M Loth… - Science translational …, 2022‏ - science.org
Triple-negative breast cancer (TNBC) is an aggressive subtype associated with early
metastatic recurrence and worse patient outcomes. TNBC tumors express molecular …

Targeting apoptosis in cancer

P Singh, B Lim - Current oncology reports, 2022‏ - Springer
Abstract Purpose of Review Apoptosis is a major mechanism of cancer cell death. Thus,
evasion of apoptosis results in therapy resistance. Here, we review apoptosis modulators in …

Pathology of triple negative breast cancer

F Borri, A Granaglia - Seminars in cancer biology, 2021‏ - Elsevier
Triple negative breast cancer (TNBC) is a subtype of breast tumor lacking hormone
receptors expression and HER2 gene amplification and represents 24% of newly diagnosed …

Triple-negative breast cancer: a brief review about epidemiology, risk factors, signaling pathways, treatment and role of artificial intelligence

NM Almansour - Frontiers in molecular biosciences, 2022‏ - frontiersin.org
Triple-negative breast cancer (TNBC) is a kind of breast cancer that lacks estrogen,
progesterone, and human epidermal growth factor receptor 2. This cancer is responsible for …

An overview of triple-negative breast cancer

P Kumar, R Aggarwal - Archives of gynecology and obstetrics, 2016‏ - Springer
Purpose Triple-negative breast cancer (TNBC) is a heterogeneous group of tumors
comprising various breast cancers simply defined by the absence of estrogen receptor …

Triple-negative breast cancer: treatment challenges and solutions

J Collignon, L Lousberg, H Schroeder… - Breast Cancer: Targets …, 2016‏ - Taylor & Francis
Triple-negative breast cancers (TNBCs) are defined by the absence of estrogen and
progesterone receptors and the absence of HER2 overexpression. These cancers represent …

[HTML][HTML] Recent therapeutic trends and promising targets in triple negative breast cancer

SY Hwang, S Park, Y Kwon - Pharmacology & therapeutics, 2019‏ - Elsevier
Breast cancer accounts for 25% of all types of cancer in women, and triple negative breast
cancer (TNBC) comprises around 15~ 20% of breast cancers. Conventional chemotherapy …

Proteomic profiling of extracellular vesicles allows for human breast cancer subty**

S Rontogianni, E Synadaki, B Li, MC Liefaard… - Communications …, 2019‏ - nature.com
Extracellular vesicles (EVs) are a potential source of disease-associated biomarkers for
diagnosis. In breast cancer, comprehensive analyses of EVs could yield robust and reliable …