Vitamin D, infections and immunity

A Ismailova, JH White - Reviews in Endocrine and Metabolic Disorders, 2022 - Springer
Vitamin D, best known for its role in skeletal health, has emerged as a key regulator of innate
immune responses to microbial threat. In immune cells such as macrophages, expression of …

Antimicrobial host defence peptides: functions and clinical potential

N Mookherjee, MA Anderson, HP Haagsman… - Nature reviews Drug …, 2020 - nature.com
Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …

[HTML][HTML] Evidence that vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths

WB Grant, H Lahore, SL McDonnell, CA Baggerly… - Nutrients, 2020 - mdpi.com
The world is in the grip of the COVID-19 pandemic. Public health measures that can reduce
the risk of infection and death in addition to quarantines are desperately needed. This article …

The role of vitamin C, vitamin D, and selenium in immune system against COVID-19

M Bae, H Kim - Molecules, 2020 - mdpi.com
Low levels of micronutrients have been associated with adverse clinical outcomes during
viral infections. Therefore, to maximize the nutritional defense against infections, a daily …

Vitamin D and immune regulation: antibacterial, antiviral, anti-inflammatory

EL Bishop, A Ismailova, S Dimeloe… - Journal of Bone and …, 2021 - academic.oup.com
Regulation of immune function continues to be one of the most well recognized extraskeletal
actions of vitamin D. This stemmed initially from the discovery that antigen presenting cells …

Putative roles of vitamin D in modulating immune response and immunopathology associated with COVID-19

R Kumar, H Rathi, A Haq, SJ Wimalawansa, A Sharma - Virus research, 2021 - Elsevier
The first incidence of COVID-19 was reported in the Wuhan city of Hubei province in China
in late December 2019. Because of failure in timely closing of borders of the affected region …

Obesity as a risk factor for COVID-19: an overview

RW Alberca, LM Oliveira, ACCC Branco… - Critical reviews in …, 2021 - Taylor & Francis
The current coronavirus disease-2019 (COVID-19) pandemic presents a huge challenge for
health-care systems worldwide. Many different risk factors are associated with disease …

[HTML][HTML] Human antimicrobial peptides as therapeutics for viral infections

A Ahmed, G Siman-Tov, G Hall, N Bhalla, A Narayanan - Viruses, 2019 - mdpi.com
Successful in vivo infection following pathogen entry requires the evasion and subversion of
multiple immunological barriers. Antimicrobial peptides (AMPs) are one of the first immune …

Modulation of the immune response to respiratory viruses by vitamin D

CL Greiller, AR Martineau - Nutrients, 2015 - mdpi.com
Background: Vitamin D deficiency has been shown to be independently associated with
increased risk of viral acute respiratory infection (ARI) in a number of observational studies …

[HTML][HTML] Neutrophils in respiratory viral infections

C Johansson, FCM Kirsebom - Mucosal immunology, 2021 - Elsevier
Viral respiratory infections are a common cause of severe disease, especially in infants,
people who are immunocompromised, and in the elderly. Neutrophils, an important innate …