Deep learning in image-based phenotypic drug discovery

D Krentzel, SL Shorte, C Zimmer - Trends in cell biology, 2023 - cell.com
Modern drug discovery approaches often use high-content imaging to systematically study
the effect on cells of large libraries of chemical compounds. By automatically screening …

[HTML][HTML] ASF-YOLO: A novel YOLO model with attentional scale sequence fusion for cell instance segmentation

M Kang, CM Ting, FF Ting, RCW Phan - Image and Vision Computing, 2024 - Elsevier
We propose a novel Attentional Scale Sequence Fusion based You Only Look Once (YOLO)
framework (ASF-YOLO) which combines spatial and scale features for accurate and fast cell …

The multimodality cell segmentation challenge: toward universal solutions

J Ma, R **e, S Ayyadhury, C Ge, A Gupta, R Gupta… - Nature …, 2024 - nature.com
Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images.
Existing cell segmentation methods are often tailored to specific modalities or require …

Opportunities and challenges for deep learning in cell dynamics research

B Chai, C Efstathiou, H Yue, VM Draviam - Trends in Cell Biology, 2024 - cell.com
The growth of artificial intelligence (AI) has led to an increase in the adoption of computer
vision and deep learning (DL) techniques for the evaluation of microscopy images and …

SCS: cell segmentation for high-resolution spatial transcriptomics

H Chen, D Li, Z Bar-Joseph - Nature methods, 2023 - nature.com
Spatial transcriptomics promises to greatly improve our understanding of tissue organization
and cell–cell interactions. While most current platforms for spatial transcriptomics only offer …

Annotation of spatially resolved single-cell data with STELLAR

M Brbić, K Cao, JW Hickey, Y Tan, MP Snyder… - Nature …, 2022 - nature.com
Accurate cell-type annotation from spatially resolved single cells is crucial to understand
functional spatial biology that is the basis of tissue organization. However, current …

Nuclei segmentation using attention aware and adversarial networks

E Goceri - Neurocomputing, 2024 - Elsevier
Accurate segmentation of nuclei plays a critical role in pathology since assessments and
diagnoses are mainly based on the recognition, measurement, and counting of nuclei …

Clusterseg: A crowd cluster pinpointed nucleus segmentation framework with cross-modality datasets

J Ke, Y Lu, Y Shen, J Zhu, Y Zhou, J Huang, J Yao… - Medical Image …, 2023 - Elsevier
The detection and segmentation of individual cells or nuclei is often involved in image
analysis across a variety of biology and biomedical applications as an indispensable …

An ensemble method with edge awareness for abnormally shaped nuclei segmentation

Y Han, Y Lei, V Shkolnikov, D **n… - Proceedings of the …, 2023 - openaccess.thecvf.com
Abnormalities in biological cell nuclei shapes are correlated with cell cycle stages, disease
states, and various external stimuli. There have been many deep learning approaches that …

Histopathological image classification with cell morphology aware deep neural networks

A Ignatov, J Yates, V Boeva - Proceedings of the IEEE/CVF …, 2024 - openaccess.thecvf.com
Histopathological images are widely used for the analysis of diseased (tumor) tissues and
patient treatment selection. While the majority of microscopy image processing was …