An up-date on Giardia and giardiasis

E Einarsson, S Ma'ayeh, SG Svärd - Current opinion in microbiology, 2016 - Elsevier
Highlights•Giardiasis is a multifactorial diarrheal disease.•Giardia infection can be protective
against other diarrheal diseases.•Giardia infection can induce IBS and chronic fatigue …

Pathogenic mechanisms of Cryptosporidium and Giardia

G Certad, E Viscogliosi, M Chabé, SM Cacciò - Trends in Parasitology, 2017 - cell.com
Intestinal protozoa are important etiological agents of diarrhea, particularly in children, yet
the public health risk they pose is often neglected. Results from the Global Enteric …

Host specificity in the Giardia duodenalis species complex

SM Caccio, M Lalle, SG Svärd - Infection, Genetics and Evolution, 2018 - Elsevier
Giardia duodenalis is a unicellular flagellated parasite that infects the gastrointestinal tract of
a wide range of mammalian species, including humans. Investigations of protein and DNA …

Behind the smile: cell biology and disease mechanisms of Giardia species

J Ankarklev, J Jerlström-Hultqvist, E Ringqvist… - Nature Reviews …, 2010 - nature.com
The eukaryotic intestinal parasite Giardia intestinalis was first described in 1681, when
Antonie van Leeuwenhoek undertook a microscopic examination of his own diarrhoeal …

Host parasite interactions and pathophysiology in Giardia infections

JA Cotton, JK Beatty, AG Buret - International journal for parasitology, 2011 - Elsevier
Giardia is a protozoan parasite of the small intestine, and a leading cause of diarrhoeal
disease worldwide in a variety of animals, including humans. The host–parasite interaction …

Advances in understanding Giardia: determinants and mechanisms of chronic sequelae

LA Bartelt, RB Sartor - F1000prime reports, 2015 - pmc.ncbi.nlm.nih.gov
Giardia lamblia is a flagellated protozoan that is the most common cause of intestinal
parasitic infection in children living in resource-limited settings. The pathogenicity of Giardia …

Giardiasis: characteristics, pathogenesis and new insights about treatment

V Vivancos, I González-Alvarez… - Current topics in …, 2018 - ingentaconnect.com
Giardia intestinalis infection causes enterocytes damage and loss of brush border of the
epithelial cells of the intestine that leads to shortening of microvilli and altered epithelial …

Characterization of the Giardia intestinalis secretome during interaction with human intestinal epithelial cells: The impact on host cells

SY Ma'ayeh, J Liu, D Peirasmaki… - PLoS neglected …, 2017 - journals.plos.org
Background Giardia intestinalis is a non-invasive protozoan parasite that causes giardiasis
in humans, the most common form of parasite-induced diarrhea. Disease mechanisms are …

The intersection of immune responses, microbiota, and pathogenesis in giardiasis

MY Fink, SM Singer - Trends in parasitology, 2017 - cell.com
Giardia lamblia is one of the most common infectious protozoans in the world. Giardia rarely
causes severe life-threatening diarrhea, and may even have a slight protective effect in this …

[HTML][HTML] The Influence of the Protozoan Giardia lamblia on the Modulation of the Immune System and Alterations in Host Glucose and Lipid Metabolism

S Klimczak, K Packi, A Rudek, S Wenclewska… - International Journal of …, 2024 - mdpi.com
Giardia lamblia, the cause of giardiasis, significantly impacts patients with metabolic
disorders related to insulin resistance (IR). Both giardiasis and metabolic disorders share …