Crosstalk between dendritic cells and regulatory T cells: Protective effect and therapeutic potential in multiple sclerosis

R Li, H Li, X Yang, H Hu, P Liu, H Liu - Frontiers in Immunology, 2022‏ - frontiersin.org
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
related to autoimmunity and is characterized by demyelination, neuroinflammation, and …

Exploring the role of interleukin-27 as a regulator of neuronal survival in central nervous system diseases

AN Nortey, KN Garces, AS Hackam - Neural regeneration …, 2022‏ - journals.lww.com
Interleukin-27 is a pleiotropic cytokine that is involved in tissue responses to infection, cell
stress, neuronal disease, and tumors. Recent studies in various tissues indicate that …

Maturation of circulating Ly6ChiCCR2+ monocytes by mannan-MOG induces antigen-specific tolerance and reverses autoimmune encephalomyelitis

A Dagkonaki, A Papalambrou, M Avloniti… - Frontiers in …, 2022‏ - frontiersin.org
Autoimmune diseases affecting the CNS not only overcome immune privilege mechanisms
that protect neural tissues but also peripheral immune tolerance mechanisms towards self …

Therapeutic role of interferon-γ in experimental autoimmune encephalomyelitis is mediated through a tolerogenic subset of splenic CD11b+ myeloid cells

G Arellano, E Acuña, E Loda, L Moore… - Journal of …, 2024‏ - Springer
Cumulative evidence has established that Interferon (IFN)-γ has both pathogenic and
protective roles in Multiple Sclerosis and the animal model, Experimental Autoimmune …

IL-27 deficiency inhibits proliferation and invasion of trophoblasts via the SFRP2/Wnt/β-catenin pathway in fetal growth restriction

XY Zhang, XY Qin, HH Shen, KT Liu… - … journal of medical …, 2023‏ - pmc.ncbi.nlm.nih.gov
Background: Fetal growth restriction (FGR) is characterized by restricted fetal growth and
dysregulated placental development. The etiology and pathogenesis still remain elusive. IL …

Stenotrophomonas-maltophilia inhibits host cellular immunity by activating PD-1/PD-L1 signaling pathway to induce T-cell exhaustion

M Wang, S Yin, Q Qin, Y Peng, Z Hu, X Zhu, L Liu… - Molecular …, 2021‏ - Elsevier
Background Smalotrophomonas maltophilia (S. maltophilia) is common in nosocomial
infections. However, few studies have revealed the effect of S. maltophilia on cellular …

[HTML][HTML] Depleting tumor cells expressing immune checkpoint ligands—A new approach to combat cancer

F Marcucci, C Rumio - Cells, 2021‏ - mdpi.com
Antibodies against inhibitory immune checkpoint molecules (ICPMs), referred to as immune
checkpoint inhibitors (ICIs), have gained a prominent place in cancer therapy. Several ICIs …

Serum cytokine profiles in myasthenia gravis with anti-muscle-specific kinase antibodies

M Yasuda, A Uzawa, Y Ozawa, Y Kojima… - Journal of …, 2023‏ - Elsevier
This study measured the serum levels of of 15 cytokines in 15 patients with anti-muscle-
specific kinase antibody-positive MG (MuSK-MG) using a multiplex suspension array …

探索白细胞介素 27 在中枢神经系统疾病中作为神经元存活调节剂的作用

AN Nortey, KN Garces, AS Hackam - **神经再生研究 (英文版), 2022‏ - sjzsyj.com.cn
Interleukin-27 is a pleiotropic cytokine that is involved in tissue responses to infection, cell
stress, neuronal disease, and tumors. Recent studies in various tissues indicate that …