Diversity of molecular targets and signaling pathways for CBD

DL de Almeida, LA Devi - Pharmacology research & …, 2020 - Wiley Online Library
Cannabidiol (CBD) is the second most abundant component of the Cannabis plant and is
known to have effects distinct from Δ9‐tetrahydrocannabinol (THC). Many studies that …

Cannabis sativa L. Bioactive Compounds and Their Protective Role in Oxidative Stress and Inflammation

DM Kopustinskiene, R Masteikova, R Lazauskas… - Antioxidants, 2022 - mdpi.com
Cannabis (Cannabis sativa L.) plants from the family Cannabidaceae have been used since
ancient times, to produce fibers, oil, and for medicinal purposes. Psychoactive delta-9 …

Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and …

EP Baron - Headache: The Journal of Head and Face Pain, 2018 - Wiley Online Library
Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology

A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

Cannabidiol (CBD) and its analogs: a review of their effects on inflammation

S Burstein - Bioorganic & medicinal chemistry, 2015 - Elsevier
First isolated from Cannabis in 1940 by Roger Adams, the structure of CBD was not
completely elucidated until 1963. Subsequent studies resulted in the pronouncement that …

Safety and side effects of cannabidiol, a Cannabis sativa constituent

M Machado Bergamaschi… - Current drug …, 2011 - ingentaconnect.com
Cannabidiol (CBD), a major nonpsychotropic constituent of Cannabis, has multiple
pharmacological actions, including anxiolytic, antipsychotic, antiemetic and anti …

[HTML][HTML] Cannabinoids and epilepsy

EC Rosenberg, RW Tsien, BJ Whalley, O Devinsky - Neurotherapeutics, 2015 - Elsevier
Cannabis has been used for centuries to treat seizures. Recent anecdotal reports,
accumulating animal model data, and mechanistic insights have raised interest in cannabis …

Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis …

EP Baron, P Lucas, J Eades, O Hogue - The journal of headache and pain, 2018 - Springer
Background Medicinal cannabis registries typically report pain as the most common reason
for use. It would be clinically useful to identify patterns of cannabis treatment in migraine and …

The effects of cannabidiol, a non-intoxicating compound of cannabis, on the cardiovascular system in health and disease

A Kicman, M Toczek - International journal of molecular sciences, 2020 - mdpi.com
Cannabidiol (CBD) is a non-intoxicating and generally well-tolerated constituent of cannabis
which exhibits potential beneficial properties in a wide range of diseases, including …

Hempseed as a nutritional resource: An overview

JC Callaway - Euphytica, 2004 - Springer
The seed of Cannabis sativa L. has been an important source of nutrition for thousands of
years in Old World cultures. Non-drug varieties of Cannabis, commonly referred to as hemp …