The neural basis of reversal learning: An updated perspective
Reversal learning paradigms are among the most widely used tests of cognitive flexibility
and have been used as assays, across species, for altered cognitive processes in a host of …
and have been used as assays, across species, for altered cognitive processes in a host of …
Functional heterogeneity within rat orbitofrontal cortex in reward learning and decision making
A Izquierdo - Journal of Neuroscience, 2017 - Soc Neuroscience
Rat orbitofrontal cortex (OFC) is located in the dorsal bank of the rhinal sulcus, and is
divided into the medial orbital area, ventral orbital area, ventrolateral orbital area, lateral …
divided into the medial orbital area, ventral orbital area, ventrolateral orbital area, lateral …
Consequences of adolescent use of alcohol and other drugs: Studies using rodent models
LP Spear - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Studies using animal models of adolescent exposure to alcohol, nicotine, cannabinoids, and
the stimulants cocaine, 3, 4-methylenedioxymethampethamine and methamphetamine have …
the stimulants cocaine, 3, 4-methylenedioxymethampethamine and methamphetamine have …
The role of the orbitofrontal cortex in alcohol use, abuse, and dependence
DE Moorman - Progress in Neuro-Psychopharmacology and …, 2018 - Elsevier
One of the major functions of the orbitofrontal cortex (OFC) is to promote flexible motivated
behavior. It is no surprise, therefore, that recent work has demonstrated a prominent impact …
behavior. It is no surprise, therefore, that recent work has demonstrated a prominent impact …
Enhancing motor learning by increasing the stability of newly formed dendritic spines in the motor cortex
Dendritic spine dynamics are thought to be substrates for motor learning and memory, and
altered spine dynamics often lead to impaired performance. Here, we describe an exception …
altered spine dynamics often lead to impaired performance. Here, we describe an exception …
Neural and behavioral mechanisms of proactive and reactive inhibition
Response inhibition is an important component of adaptive behavior. Substantial prior
research has focused on reactive inhibition, which refers to the cessation of a motor …
research has focused on reactive inhibition, which refers to the cessation of a motor …
Cyfip1 haploinsufficient rats show white matter changes, myelin thinning, abnormal oligodendrocytes and behavioural inflexibility
The biological basis of the increased risk for psychiatric disorders seen in 15q11. 2 copy
number deletion is unknown. Previous work has shown disturbances in white matter tracts in …
number deletion is unknown. Previous work has shown disturbances in white matter tracts in …
The mouse prefrontal cortex: Unity in diversity
The prefrontal cortex (PFC) is considered to constitute the highest stage of neural integration
and to be devoted to representation and production of actions. Studies in primates have laid …
and to be devoted to representation and production of actions. Studies in primates have laid …
Neural index of reinforcement learning predicts improved stimulus–response retention under high working memory load
Human learning and decision-making are supported by multiple systems operating in
parallel. Recent studies isolating the contributions of reinforcement learning (RL) and …
parallel. Recent studies isolating the contributions of reinforcement learning (RL) and …
Infralimbic cortex is required for learning alternatives to prelimbic promoted associations through reciprocal connectivity
A Mukherjee, P Caroni - Nature communications, 2018 - nature.com
Prefrontal cortical areas mediate flexible adaptive control of behavior, but the specific
contributions of individual areas and the circuit mechanisms through which they interact to …
contributions of individual areas and the circuit mechanisms through which they interact to …