Inorganic nanomaterials with rapid clearance for biomedical applications
Inorganic nanomaterials that have inherently exceptional physicochemical properties (eg,
catalytic, optical, thermal, electrical, or magnetic performance) that can provide desirable …
catalytic, optical, thermal, electrical, or magnetic performance) that can provide desirable …
Designing bioresponsive nanomaterials for intracellular self-assembly
Supramolecular assemblies are essential components of living organisms. Cellular
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …
Metal-free bioorthogonal click chemistry in cancer theranostics
Bioorthogonal chemistry is a powerful tool to site-specifically activate drugs in living systems.
Bioorthogonal reactions between a pair of biologically reactive groups can rapidly and …
Bioorthogonal reactions between a pair of biologically reactive groups can rapidly and …
Dual key co-activated nanoplatform for switchable MRI monitoring accurate ferroptosis-based synergistic therapy
R Yue, C Zhang, L Xu, Y Wang, G Guan, L Lei, X Zhang… - Chem, 2022 - cell.com
Ferroptosis is of great significance for disease treatment and drug design because of its
effective damage to drug-resistant cells. However, ferroptosis-based therapy presents …
effective damage to drug-resistant cells. However, ferroptosis-based therapy presents …
Furin‐instructed intracellular gold nanoparticle aggregation for tumor photothermal therapy
J Chen, Y Ma, W Du, T Dai, Y Wang… - Advanced Functional …, 2020 - Wiley Online Library
Today, exploring ideal photothermal agents (PTAs) for effective photothermal therapy (PTT)
of cancer is an important issue. Cancer‐related enzyme‐instructed aggregation of gold …
of cancer is an important issue. Cancer‐related enzyme‐instructed aggregation of gold …
A Telomerase-Activated Magnetic Resonance Imaging Probe for Consecutively Monitoring Tumor Growth Kinetics and In Situ Screening Inhibitors
J Dai, Z Liu, L Wang, G Huang, S Song… - Journal of the …, 2023 - ACS Publications
Telomerase has long been considered as a biomarker for cancer diagnosis and a
therapeutic target for drug discovery. Detecting telomerase activity in vivo could provide …
therapeutic target for drug discovery. Detecting telomerase activity in vivo could provide …
Dual‐Responsive Turn‐On T1 Imaging‐Guided Mild Photothermia for Precise Apoptotic Cancer Therapy
S Song, Q Wang, J **e, J Dai, D Ouyang… - Advanced …, 2023 - Wiley Online Library
Apoptosis has gained increasing attention in cancer therapy as an intrinsic signaling
pathway, which leads to minimal leakage of waste products from a dying cell to neighboring …
pathway, which leads to minimal leakage of waste products from a dying cell to neighboring …
Fluorescence probes for sensing and imaging within Golgi apparatus
H Wang, X Zhang, T **u, H Wang, P Li… - Coordination Chemistry …, 2024 - Elsevier
As a crucial constituent of the endomembrane system in eukaryotic cells, the Golgi
apparatus serves as a major transport hub for intracellular macromolecular transport. Its …
apparatus serves as a major transport hub for intracellular macromolecular transport. Its …
Microwave absorption-based magnetic liquid metal nano-missiles for thermodynamic/immunological cascade hepatoma therapy
Microwave ablation (MWA) therapy, as a local tumor hyperthermia technology, holds great
promise for hepatoma treatment. However, the extensive clinical application of the MWA …
promise for hepatoma treatment. However, the extensive clinical application of the MWA …
Hsp70‐targeting and size‐tunable nanoparticles combine with PD‐1 checkpoint blockade to treat glioma
R **e, Y Wang, F Tong, W Yang, T Lei, Y Du, X Wang… - Small, 2023 - Wiley Online Library
Invasive glioma usually disrupts the integrity of the blood‐brain barrier (BBB), making the
delivery of nanodrugs across the BBB possible, but sufficient targeting ability is still avidly …
delivery of nanodrugs across the BBB possible, but sufficient targeting ability is still avidly …