Gamma-aminobutyric acid as a potential postbiotic mediator in the gut–brain axis

JD Braga, M Thongngam, T Kumrungsee - npj Science of Food, 2024 - nature.com
Gamma-aminobutyric acid (GABA) plays a crucial role in the central nervous system as an
inhibitory neurotransmitter. Imbalances of this neurotransmitter are associated with …

Neuroinflammation as a risk factor for attention deficit hyperactivity disorder

GA Dunn, JT Nigg, EL Sullivan - Pharmacology Biochemistry and Behavior, 2019 - Elsevier
Abstract Attention Deficit Hyperactivity Disorder (ADHD) is a persistent, and impairing
pediatric-onset neurodevelopmental condition. Its high prevalence, and recurrent …

[HTML][HTML] GABA-receptive microglia selectively sculpt develo** inhibitory circuits

E Favuzzi, S Huang, GA Saldi, L Binan, LA Ibrahim… - Cell, 2021 - cell.com
Microglia, the resident immune cells of the brain, have emerged as crucial regulators of
synaptic refinement and brain wiring. However, whether the remodeling of distinct synapse …

Iron deficiency, cognitive functions, and neurobehavioral disorders in children

L Pivina, Y Semenova, MD Doşa… - Journal of molecular …, 2019 - Springer
More than 25% of the world's population is affected by anemia, of which more than 50%
suffers from iron deficiency anemia (IDA). Children below 7 years of age are the population …

Reduced GABA and altered somatosensory function in children with autism spectrum disorder

NAJ Puts, EL Wodka, AD Harris, D Crocetti… - Autism …, 2017 - Wiley Online Library
Background: Abnormal responses to tactile stimuli are a common feature of autism spectrum
disorder (ASD). Several lines of evidence suggest that GABAergic function, which has a …

Reduced microbiome alpha diversity in young patients with ADHD

A Prehn-Kristensen, A Zimmermann, L Tittmann… - PloS one, 2018 - journals.plos.org
ADHD is a psychiatric disorder which is characterized by hyperactivity, impulsivity and
attention problems. Due to recent findings of microbial involvement in other psychiatric …

Gannet: A batch‐processing tool for the quantitative analysis of gamma‐aminobutyric acid–edited MR spectroscopy spectra

RAE Edden, NAJ Puts, AD Harris… - Journal of magnetic …, 2014 - Wiley Online Library
Purpose The purpose of this study is to describe the Gannet toolkit for the quantitative batch
analysis of gamma‐aminobutyric acid (GABA)‐edited MRS data. Materials and Methods …

Brain GABA levels across psychiatric disorders: A systematic literature review and meta‐analysis of 1H‐MRS studies

RR Schür, LWR Draisma, JP Wijnen… - Human brain …, 2016 - Wiley Online Library
The inhibitory gamma‐aminobutyric acid (GABA) system is involved in the etiology of most
psychiatric disorders, including schizophrenia, autism spectrum disorder (ASD) and major …

An overview on neurobiology and therapeutics of attention-deficit/hyperactivity disorder

BS Da Silva, EH Grevet, LCF Silva, JKN Ramos… - Discover Mental …, 2023 - Springer
Abstract Attention-Deficit/Hyperactivity Disorder (ADHD) is a prevalent psychiatric condition
characterized by developmentally inappropriate symptoms of inattention and/or …

[HTML][HTML] Behavioral and cognitive correlates of the aperiodic (1/f-like) exponent of the EEG power spectrum in adolescents with and without ADHD

BD Ostlund, BR Alperin, T Drew… - Developmental cognitive …, 2021 - Elsevier
Efficient information processing facilitates cognition and may be disrupted in a number of
neurodevelopmental conditions. And yet, the role of inefficient information processing and its …