Poloxamer: A versatile tri-block copolymer for biomedical applications
Poloxamers, also called Pluronic, belong to a unique class of synthetic tri-block copolymers
containing central hydrophobic chains of poly (propylene oxide) sandwiched between two …
containing central hydrophobic chains of poly (propylene oxide) sandwiched between two …
Cancer nanotechnology: a new revolution for cancer diagnosis and therapy
Background: Nanotechnology is gaining significant attention worldwide for cancer treatment.
Nanobiotechnology encourages the combination of diagnostics with therapeutics, which is a …
Nanobiotechnology encourages the combination of diagnostics with therapeutics, which is a …
Biocompatibility and safety of PLA and its copolymers
PLA and its copolymers are commonly used for a wide variety of applications. While they are
considered to be biocompatible, side effects resulting from their implantation have been …
considered to be biocompatible, side effects resulting from their implantation have been …
Polymeric mixed micelles as nanomedicines: Achievements and perspectives
M Cagel, FC Tesan, E Bernabeu, MJ Salgueiro… - European Journal of …, 2017 - Elsevier
During the past few decades, polymeric micelles have raised special attention as novel
nano-sized drug delivery systems for optimizing the treatment and diagnosis of numerous …
nano-sized drug delivery systems for optimizing the treatment and diagnosis of numerous …
Oral empagliflozin-loaded tri-layer core-sheath fibers fabricated using tri-axial electrospinning: enhanced in vitro and in vivo antidiabetic performance
Empagliflozin (EM) was successfully loaded in polycaprolactone/poly (L-lactic
acid)/polymethyl methacrylate (PCL/PLA/PMMA) fibers. In the rat β-cell line (BRIN-BD11) …
acid)/polymethyl methacrylate (PCL/PLA/PMMA) fibers. In the rat β-cell line (BRIN-BD11) …
Nanocarrier for poorly water-soluble anticancer drugs—barriers of translation and solutions
M Narvekar, HY Xue, JY Eoh, HL Wong - Aaps Pharmscitech, 2014 - Springer
Many existing chemotherapeutic drugs, repurposed drugs and newly developed small-
molecule anticancer compounds have high lipophilicity and low water-solubility. Currently …
molecule anticancer compounds have high lipophilicity and low water-solubility. Currently …
Tumor microenvironment targeted nanotherapy
Recent developments in nanotechnology have brought new approaches to cancer
diagnosis and therapy. While enhanced permeability and retention effect promotes nano …
diagnosis and therapy. While enhanced permeability and retention effect promotes nano …
Advanced imaging techniques for tracking drug dynamics at the subcellular level
Optical microscopes are an important imaging tool that have effectively advanced the
development of modern biomedicine. In recent years, super-resolution microscopy (SRM) …
development of modern biomedicine. In recent years, super-resolution microscopy (SRM) …
Self-assembled nanoparticles based on hyaluronic acid-ceramide (HA-CE) and Pluronic® for tumor-targeted delivery of docetaxel
Hyaluronic acid-ceramide (HA-CE)-based self-assembled nanoparticles were developed for
intravenous docetaxel (DCT) delivery. In this study, physicochemical properties, cellular …
intravenous docetaxel (DCT) delivery. In this study, physicochemical properties, cellular …
Polymeric nanomicelles of curcumin: Potential applications in cancer
Natural compounds, primarily derived from plants, have been isolated and evaluated as
alternative and complementary treatments for cancer. Curcumin has been proven to be …
alternative and complementary treatments for cancer. Curcumin has been proven to be …