Network pharmacology prediction and molecular docking-based strategy to explore the potential mechanism of Huanglian Jiedu Decoction against sepsis
X Li, S Wei, S Niu, X Ma, H Li, M **g, Y Zhao - Computers in biology and …, 2022 - Elsevier
Abstract Background Huanglian Jiedu Decoction (HLJDD) is a classical herbal formula with
potential efficacy in the treatment of sepsis. However, the main components and potential …
potential efficacy in the treatment of sepsis. However, the main components and potential …
Modern approaches in the discovery and development of plant-based natural products and their analogues as potential therapeutic agents
Natural products represents an important source of new lead compounds in drug discovery
research. Several drugs currently used as therapeutic agents have been developed from …
research. Several drugs currently used as therapeutic agents have been developed from …
A Comprehensive Review on Cannabis sativa Ethnobotany, Phytochemistry, Molecular Docking and Biological Activities
For more than a century, Cannabis was considered a narcotic and has been banned by
lawmakers all over the world. In recent years, interest in this plant has increased due to its …
lawmakers all over the world. In recent years, interest in this plant has increased due to its …
[HTML][HTML] The role and potential of computer-aided drug discovery strategies in the discovery of novel antimicrobials
Antimicrobial resistance (AMR) has become more of a concern in recent decades,
particularly in infections associated with global public health threats. The development of …
particularly in infections associated with global public health threats. The development of …
Using Network Pharmacology and Molecular Docking to Explore the Mechanism of Shan Ci Gu (Cremastra appendiculata) Against Non-Small Cell Lung Cancer
Y Wang, Y Zhang, Y Wang, X Shu, C Lu, S Shao… - Frontiers in …, 2021 - frontiersin.org
Background: In recent years, the incidence and mortality rates of non-small cell lung cancer
(NSCLC) have increased significantly. Shan Ci Gu is commonly used as an anticancer drug …
(NSCLC) have increased significantly. Shan Ci Gu is commonly used as an anticancer drug …
Immune-Enhancing Effects of a Novel Glucan from Purple Sweet Potato Ipomoea batatas (L.) Lam on RAW264.7 Macrophage Cells via TLR2- and TLR4-Mediated …
C Ji, Z Zhang, J Chen, D Song, B Liu, J Li… - Journal of Agricultural …, 2021 - ACS Publications
PSPP-1 was obtained from purple sweet potato, and the effects of PSPP-1 on the immune
modulation on macrophage cells were investigated for the first time. PSPP-1 promoted …
modulation on macrophage cells were investigated for the first time. PSPP-1 promoted …
[PDF][PDF] Natural Products As Sources of Drug Discovery: Exploration, Optimisation, and Translation Into Clinical Practice
This paper features the significance of regular items in drug disclosure, featuring their
assorted synthetic designs and natural exercises. It underscores the requirement for a …
assorted synthetic designs and natural exercises. It underscores the requirement for a …
Synthesis of thiazolidine-2, 4-dione tethered 1, 2, 3-triazoles as α-amylase inhibitors: in vitro approach coupled with QSAR, molecular docking, molecular dynamics …
A new series of thiazolidine-2, 4-dione tethered 1, 2, 3-triazole derivatives were designed,
synthesized and screened for their α-amylase inhibitory potential employing in vitro and in …
synthesized and screened for their α-amylase inhibitory potential employing in vitro and in …
[HTML][HTML] Production of fucoxanthin from microalgae Isochrysis galbana of Djibouti: Optimization, correlation with antioxidant potential, and bioinformatics approaches
Fucoxanthin, a carotenoid with remarkable antioxidant properties, has considerable
potential for high-value biotechnological applications in the pharmaceutical, nutraceutical …
potential for high-value biotechnological applications in the pharmaceutical, nutraceutical …
Applying molecular docking to pesticides
Y Hou, Y Bai, C Lu, Q Wang, Z Wang… - Pest Management …, 2023 - Wiley Online Library
Pesticide creation is related to the development of sustainable agricultural and ecological
safety, and molecular docking technology can effectively help in pesticide innovation. This …
safety, and molecular docking technology can effectively help in pesticide innovation. This …