Major review: Molecular genetics of primary open-angle glaucoma
Glaucoma is a leading cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), the most common type, is a complex inherited disorder that is …
glaucoma (POAG), the most common type, is a complex inherited disorder that is …
The role of long noncoding RNAs in neurodegenerative diseases
P Wan, W Su, Y Zhuo - Molecular neurobiology, 2017 - Springer
Long noncoding RNAs (lncRNAs) are transcripts with low protein-coding potential but
occupy a large part of transcriptional output. Their roles include regulating gene expression …
occupy a large part of transcriptional output. Their roles include regulating gene expression …
Neuroinflammation in primary open-angle glaucoma
S Vernazza, S Tirendi, AM Bassi, CE Traverso… - Journal of clinical …, 2020 - mdpi.com
Primary open-angle glaucoma (POAG) is the second leading cause of irreversible blindness
worldwide. Increasing evidence suggests oxidative damage and immune response defects …
worldwide. Increasing evidence suggests oxidative damage and immune response defects …
[HTML][HTML] Cell cycle deficits in neurodegenerative disorders: uncovering molecular mechanisms to drive innovative therapeutic development
Cell cycle dysregulation has been implicated in the pathogenesis of neurodegenerative
disorders. Specialised function obligates neuronal cells to subsist in a quiescent state of cell …
disorders. Specialised function obligates neuronal cells to subsist in a quiescent state of cell …
Epigenetics and signaling pathways in glaucoma
AC Gauthier, J Liu - BioMed research international, 2017 - Wiley Online Library
Glaucoma is the most common cause of irreversible blindness worldwide. This
neurodegenerative disease becomes more prevalent with aging, but predisposing genetic …
neurodegenerative disease becomes more prevalent with aging, but predisposing genetic …
[HTML][HTML] Open angle glaucoma
Objectives: Identify risk factors and early signs of open-angle glaucoma during routine
patient evaluations. Differentiate between open-angle glaucoma and other ocular conditions …
patient evaluations. Differentiate between open-angle glaucoma and other ocular conditions …
Glaucoma genes and mechanisms
JL Wiggs - Progress in molecular biology and translational …, 2015 - Elsevier
Genetic studies have yielded important genes contributing to both early-onset and adult-
onset forms of glaucoma. The proteins encoded by the current collection of glaucoma genes …
onset forms of glaucoma. The proteins encoded by the current collection of glaucoma genes …
[HTML][HTML] Altered amplitude of low-frequency fluctuation in primary open-angle glaucoma: a resting-state FMRI study
T Li, Z Liu, J Li, Z Liu, Z Tang, X **e… - … & visual science, 2015 - jov.arvojournals.org
Purpose.: To analyze the altered amplitude of low-frequency fluctuation (ALFF) of the brain
using resting-state functional magnetic resonance imaging (fMRI) in patients with primary …
using resting-state functional magnetic resonance imaging (fMRI) in patients with primary …
Diabetic retinopathy, lncRNAs, and inflammation: a dynamic, interconnected network
Diabetic retinopathy (DR) is reaching epidemic levels globally due to the increase in
prevalence of diabetes mellitus (DM). DR also has detrimental effects to quality of life, as it is …
prevalence of diabetes mellitus (DM). DR also has detrimental effects to quality of life, as it is …
Genetic architecture of primary open-angle glaucoma in individuals of African descent: the African Descent and Glaucoma Evaluation Study III
Purpose To find genetic contributions to glaucoma in African Americans. Design Cross-
sectional, case-control study. Participants One thousand eight hundred seventy-five primary …
sectional, case-control study. Participants One thousand eight hundred seventy-five primary …