Current advance of nanotechnology in diagnosis and treatment for malignant tumors
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
Extrahepatic targeting of lipid nanoparticles in vivo with intracellular targeting for future nanomedicines
T Nakamura, Y Sato, Y Yamada… - Advanced drug delivery …, 2022 - Elsevier
A new era of nanomedicines that involve nucleic acids/gene therapy has been opened after
two decades in 21st century and new types of more efficient drug delivery systems (DDS) …
two decades in 21st century and new types of more efficient drug delivery systems (DDS) …
mRNA nanodelivery systems: targeting strategies and administration routes
M Yuan, Z Han, Y Liang, Y Sun, B He… - Biomaterials …, 2023 - spj.science.org
With the great success of coronavirus disease (COVID-19) messenger ribonucleic acid
(mRNA) vaccines, mRNA therapeutics have gained significant momentum for the prevention …
(mRNA) vaccines, mRNA therapeutics have gained significant momentum for the prevention …
Expanding RNAi to kidneys, lungs, and spleen via selective ORgan targeting (SORT) siRNA lipid nanoparticles
Inhibition of disease‐causing mutations using RNA interference (RNAi) has resulted in
clinically approved medicines with additional candidates in late stage trials. However …
clinically approved medicines with additional candidates in late stage trials. However …
An overview of the stability and delivery challenges of commercial nucleic acid therapeutics
RG Ingle, WJ Fang - Pharmaceutics, 2023 - mdpi.com
Nucleic acid (NA)-based biopharmaceuticals have emerged as promising therapeutic
modalities. NA therapeutics are a diverse class of RNA and DNA and include antisense …
modalities. NA therapeutics are a diverse class of RNA and DNA and include antisense …
Inhaled drug delivery: Past, present, and future
Inhaled drug delivery has been an emerging route for the treatment of lung diseases with
clear advantages over oral and intravenous routes. However, the delivery efficacy is affected …
clear advantages over oral and intravenous routes. However, the delivery efficacy is affected …
Nebulized Inhalation of Peptide-Modified DNA Origami To Alleviate Acute Lung Injury
H Wang, Y Jiao, S Ma, Z Li, J Gong, Q Jiang… - Nano Letters, 2024 - ACS Publications
Acute lung injury (ALI) is a severe inflammatory lung disease, with high mortality rates. Early
intervention by reactive oxygen species (ROS) scavengers could reduce ROS accumulation …
intervention by reactive oxygen species (ROS) scavengers could reduce ROS accumulation …
Progress on the pathological tissue microenvironment barrier-modulated nanomedicine
H Han, L **ng, BT Chen, Y Liu, TJ Zhou, Y Wang… - Advanced Drug Delivery …, 2023 - Elsevier
Imbalance in the tissue microenvironment is the main obstacle to drug delivery and
distribution in the human body. Before penetrating the pathological tissue microenvironment …
distribution in the human body. Before penetrating the pathological tissue microenvironment …
Recent progress of iron-based nanomaterials in gene delivery and tumor gene therapy
Y Gong, X Hu, M Chen, J Wang - Journal of Nanobiotechnology, 2024 - Springer
Gene therapy aims to modify or manipulate gene expression and change the biological
characteristics of living cells to achieve the purpose of treating diseases. The safe, efficient …
characteristics of living cells to achieve the purpose of treating diseases. The safe, efficient …
[HTML][HTML] Aerosol delivery of star polymer-siRNA nanoparticles as a therapeutic strategy to inhibit lung tumor growth
Lung cancer is a major contributor to cancer-related death worldwide. siRNA
nanomedicines are powerful tools for cancer therapeutics. However, there are challenges to …
nanomedicines are powerful tools for cancer therapeutics. However, there are challenges to …