Aims Frailty is a complex geriatric syndrome resulting in decreased physiological reserves.
Frailty and polypharmacy are common in older adults and the focus of extensive studies …

Background Older people living with frailty are often exposed to polypharmacy and potential
harm from medications. Targeted deprescribing in this population represents an important …

Objective Polypharmacy is the concomitant use of several drugs by a single person, and it
increases the risk of adverse drug-related events in older adults. Little is known about the …

The International Conference on Harmonization considers older people a 'special
population', as they differ from younger adults in terms of comorbidity, polypharmacy …

Objective: To identify how 'elderly'patients are defined and considered within Australian
clinical guidelines for the use of pharmacotherapy. Method: Guidelines pertaining to the use …

Background Increasingly, patient medication adherence data are being consolidated from
claims databases and electronic health records (EHRs). Such databases offer an indirect …

Objectives To investigate the relationship between polypharmacy and frailty. Design
Longitudinal, observational cohort study. Setting Saarland, Germany. Participants 3,058 …

Purpose To assess the prevalence of polypharmacy and frailty, to examine their association,
and to establish their independent and combined effects on mortality in a sample of French …

Background Multi-morbidity and polypharmacy increase the risk of non-trivial adverse drug
reactions (ADRs) in older people during hospitalization. Despite this, there are no …

Medication adherence is a key factor of the therapy of chronic diseases in older people with
chronic diseases. Inadequate health literacy results in poor health outcomes. Therefore, the …