Role of the gut microbiota in anticancer therapy: from molecular mechanisms to clinical applications

LY Zhao, JX Mei, G Yu, L Lei, WH Zhang… - … and Targeted Therapy, 2023 - nature.com
In the past period, due to the rapid development of next-generation sequencing technology,
accumulating evidence has clarified the complex role of the human microbiota in the …

Chlamydia cell biology and pathogenesis

C Elwell, K Mirrashidi, J Engel - Nature Reviews Microbiology, 2016 - nature.com
Chlamydia spp. are important causes of human disease for which no effective vaccine
exists. These obligate intracellular pathogens replicate in a specialized membrane …

Chlamydia trachomatis genital infections

CM O'Connell, ME Ferone - Microbial cell, 2016 - pmc.ncbi.nlm.nih.gov
Etiology, transmission and protection: Chlamydia trachomatis is the leading cause of
bacterial sexually transmitted infection (STI) globally. However, C. trachomatis also causes …

Bacterial‐mediated tumor therapy: old treatment in a new context

Y Liu, L Niu, N Li, Y Wang, M Liu, X Su, X Bao… - Advanced …, 2023 - Wiley Online Library
Targeted therapy and immunotherapy have brought hopes for precision cancer treatment.
However, complex physiological barriers and tumor immunosuppression result in poor …

Salmonella manipulation of host signaling pathways provokes cellular transformation associated with gallbladder carcinoma

T Scanu, RM Spaapen, JM Bakker, CB Pratap, L Wu… - Cell host & …, 2015 - cell.com
Cancer is fueled by deregulation of signaling pathways in control of cellular growth and
proliferation. These pathways are also targeted by infectious pathogens en route to …

[HTML][HTML] The role of inflammation and inflammatory mediators in the development, progression, metastasis, and chemoresistance of epithelial ovarian cancer

SS Savant, S Sriramkumar, HM O'Hagan - Cancers, 2018 - mdpi.com
Inflammation plays a role in the initiation and development of many types of cancers,
including epithelial ovarian cancer (EOC) and high grade serous ovarian cancer (HGSC), a …

Alterations of Vaginal Microbiota and Chlamydia trachomatis as Crucial Co-Causative Factors in Cervical Cancer Genesis Procured by HPV

C Gargiulo Isacco, MG Balzanelli, S Garzone… - Microorganisms, 2023 - mdpi.com
Chlamydia trachomatis and human papillomavirus (HPV) are the most common pathogens
found in sexually transmitted infections (STIs), and both are known to increase the risk of …

Collateral damage: insights into bacterial mechanisms that predispose host cells to cancer

A Gagnaire, B Nadel, D Raoult, J Neefjes… - Nature Reviews …, 2017 - nature.com
Infections are estimated to contribute to 20% of all human tumours. Viruses are known to
induce cell transformation, but evidence has also linked bacteria, such as Helicobacter …

The cervicovaginal microbiota-host interaction modulates Chlamydia trachomatis infection

VL Edwards, SB Smith, EJ McComb, J Tamarelle, B Ma… - MBio, 2019 - journals.asm.org
The mechanism (s) by which Lactobacillus-dominated cervicovaginal microbiota provide a
barrier to Chlamydia trachomatis infection remain (s) unknown. Here we evaluate the impact …

Structural change in microbiota by a probiotic cocktail enhances the gut barrier and reduces cancer via TLR2 signaling in a rat model of colon cancer

ED Kuugbee, X Shang, Y Gamallat, D Bamba… - Digestive diseases and …, 2016 - Springer
Background Structural change in the gut microbiota is implicated in cancer. The beneficial
modulation of the microbiota composition with probiotics and prebiotics prevents diseases …