Effective intraocular drug delivery poses a major challenge due to the presence of various
elimination mechanisms and physiological barriers that result in low ocular bioavailability …

Research in the development of ophthalmic drug formulations and innovative technologies
over the past few decades has been directed at improving the penetration of medications …

Polymeric in situ forming depots have emerged as highly promising drug delivery systems
for long-acting applications. Their effectiveness is attributed to essential characteristics such …

Amphiphilic block copolymers are widely utilized in the design of formulations owing to their
unique physicochemical properties, flexible structures and functional chemistry. Amphiphilic …

Introduction: Topical administration is the favored route for local delivery of therapeutic
agents due to its convenience and affordability. The specific challenge of designing a …

Invasive fungal infections are becoming a major health concern in several groups of patients
leading to severe morbidity and mortality. Moreover, cutaneous fungal infections are a major …

The eye is a directly accessible sensitive organ, impairment of which causes direct effect on
the quality of life. Efficient ocular drug delivery remains a major challenge for the …

This review focuses on synthetic and natural amphiphilic systems prepared from straight-
chain and macrocyclic compounds capable of self-assembly with the formation of nanoscale …

Respiratory diseases have remained one of the most common diseases worldwide, in which
oral and intravenous administration are the most common treatment routes. However, these …

Tacrolimus (FK506) was used to prevent corneal allograft rejection in patients who were
resistant to steroids and cyclosporine. However, the formulation for FK506 ocular delivery …