[HTML][HTML] Desaturases and elongases involved in long-chain polyunsaturated fatty acid biosynthesis in aquatic animals: From genes to functions

Ó Monroig, AC Shu-Chien, N Kabeya, DR Tocher… - Progress in lipid …, 2022 - Elsevier
Marine ecosystems are rich in “omega-3” long-chain (C 20-24) polyunsaturated fatty acids
(LC-PUFA). Their production has been historically accepted to derive mostly from marine …

Long-chain polyunsaturated fatty acid biosynthesis in chordates: Insights into the evolution of Fads and Elovl gene repertoire

LFC Castro, DR Tocher, O Monroig - Progress in lipid research, 2016 - Elsevier
Long-chain polyunsaturated fatty acids (LC-PUFA) are major components of complex lipid
molecules and are also involved in numerous critical biological processes. Studies …

Regulation of long-chain polyunsaturated fatty acid biosynthesis in teleost fish

D **e, C Chen, Y Dong, C You, S Wang… - Progress in Lipid …, 2021 - Elsevier
Abstract Omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA, C 20-24),
including eicosapentaenoic acid (EPA, 20: 5n-3) and docosahexaenoic acid (DHA, 22: 6n …

Fatty acid requirements in ontogeny of marine and freshwater fish

DR Tocher - Aquaculture research, 2010 - Wiley Online Library
Essential fatty acid (EFA) requirements vary qualitatively and quantitatively with both species
and during ontogeny of fish, with early developmental stages and broodstock being critical …

Fish oil replacement in finfish nutrition

GM Turchini, BE Torstensen, WK Ng - Reviews in aquaculture, 2009 - Wiley Online Library
Unsustainable fishing practices have placed a heavy emphasis on aquaculture to meet the
global shortfalls in the supply of fish and seafood, which are commonly accepted as the …

Biosynthesis of polyunsaturated fatty acids in marine invertebrates: recent advances in molecular mechanisms

Ó Monroig, DR Tocher, JC Navarro - Marine drugs, 2013 - mdpi.com
Virtually all polyunsaturated fatty acids (PUFA) originate from primary producers but can be
modified by bioconversions as they pass up the food chain in a process termed trophic …

[書籍][B] Fish oil replacement and alternative lipid sources in aquaculture feeds

GM Turchini, WK Ng, DR Tocher - 2010 - taylorfrancis.com
Experts are predicting that demand for marine fish oil will soon outstrip supply, creating
extreme urgency within the global aquafeed industry to find viable alternatives. Fish Oil …

Vertebrate fatty acyl desaturase with Δ4 activity

Y Li, O Monroig, L Zhang, S Wang… - Proceedings of the …, 2010 - National Acad Sciences
Biosynthesis of the highly biologically active long-chain polyunsaturated fatty acids,
arachidonic (ARA), eicosapentaenoic (EPA), and docosahexaenoic (DHA) acids, in …

Biosynthesis of polyunsaturated fatty acids in aquatic ecosystems: general pathways and new directions

MV Bell, DR Tocher - Lipids in aquatic ecosystems, 2009 - Springer
It is now well established that the long-chain, omega-3 (ω3 or n-3) polyunsaturated fatty
acids (PUFA) are vitally important in human nutrition, reflecting their particular roles in critical …

Novel cellular functions of very long chain-fatty acids: insight from ELOVL4 mutations

F Deák, RE Anderson, JL Fessler… - Frontiers in cellular …, 2019 - frontiersin.org
Elongation of Very Long chain fatty acids-4 (ELOVL4) protein is a member of the ELOVL
family of fatty acid elongases that is collectively responsible for catalyzing formation of long …