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The functional meaning of 5′ UTR in protein-coding genes
As it is well known, messenger RNA has many regulatory regions along its sequence length.
One of them is the 5′ untranslated region (5'UTR), which itself contains many regulatory …
One of them is the 5′ untranslated region (5'UTR), which itself contains many regulatory …
Mitochondrial dysfunction and Parkinson's disease: pathogenesis and therapeutic strategies
Parkinson's disease (PD) is a common age-related neurodegenerative disorder whose
pathogenesis is not completely understood. Mitochondrial dysfunction and increased …
pathogenesis is not completely understood. Mitochondrial dysfunction and increased …
The interplay of signaling pathways and miRNAs in the pathogenesis and targeted therapy of esophageal cancer
Globally, esophageal cancer (EC) is the 6th leading cause of cancer-related deaths and the
second deadliest gastrointestinal cancer. Multiple genetic and epigenetic factors, such as …
second deadliest gastrointestinal cancer. Multiple genetic and epigenetic factors, such as …
miRNAs orchestration of gallbladder cancer–particular emphasis on diagnosis, progression and drug resistance
Gallbladder cancer (GBC) is characterized by a highly invasive nature and a poor prognosis,
with adenocarcinoma being the main histological subtype. According to statistical data …
with adenocarcinoma being the main histological subtype. According to statistical data …
The potential role of miRNAs in the pathogenesis of cardiovascular diseases–a focus on signaling pathways interplay
For the past two decades since their discovery, scientists have linked microRNAs (miRNAs)
to posttranscriptional regulation of gene expression in critical cardiac physiological and …
to posttranscriptional regulation of gene expression in critical cardiac physiological and …
Unraveling the role of miRNAs in the diagnosis, progression, and therapeutic intervention of Alzheimer's disease
Alzheimer's disease (AD) is a multifaceted, advancing neurodegenerative illness that is
responsible for most cases of neurological impairment and dementia in the aged population …
responsible for most cases of neurological impairment and dementia in the aged population …
miRNAs as potential game-changers in retinoblastoma: Future clinical and medicinal uses
Retinoblastoma (RB) is a rare tumor in children, but it is the most common primitive
intraocular malignancy in childhood age, especially those below three years old. The RB …
intraocular malignancy in childhood age, especially those below three years old. The RB …
miRNAs orchestration of salivary gland cancer-Particular emphasis on diagnosis, progression, and drug resistance
Cancer of the salivary glands is one of the five major types of head and neck cancer. Due to
radioresistance and a strong propensity for metastasis, the survival rate for nonresectable …
radioresistance and a strong propensity for metastasis, the survival rate for nonresectable …
Melodic maestros: unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of malignant pleural mesothelioma
MA Abd-Elmawla, SSA Mageed… - … -Research and Practice, 2023 - Elsevier
Malignant pleural mesothelioma (MPM) is a highly lethal form of pleural cancer
characterized by a scarcity of effective therapeutic interventions, resulting in unfavorable …
characterized by a scarcity of effective therapeutic interventions, resulting in unfavorable …
Plasma miRNA profile at COVID-19 onset predicts severity status and mortality
A Fernández-Pato, A Virseda-Berdices… - Emerging microbes & …, 2022 - Taylor & Francis
Background MicroRNAs (miRNAs) have a crucial role in regulating immune response
against infectious diseases, showing changes early in disease onset and before the …
against infectious diseases, showing changes early in disease onset and before the …