Coronavirus biology and replication: implications for SARS-CoV-2

P V'kovski, A Kratzel, S Steiner, H Stalder… - Nature Reviews …, 2021 - nature.com
The SARS-CoV-2 pandemic and its unprecedented global societal and economic disruptive
impact has marked the third zoonotic introduction of a highly pathogenic coronavirus into the …

Therapeutic options for the 2019 novel coronavirus (2019-nCoV)

G Li, E De Clercq - Nature reviews Drug discovery, 2020 - nature.com
Therapeutic options for the 2019 novel coronavirus (2019-nCoV) Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Coronavirus infections in children including COVID-19: an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children

P Zimmermann, N Curtis - The Pediatric infectious disease journal, 2020 - journals.lww.com
Coronaviruses (CoVs) are a large family of enveloped, single-stranded, zoonotic RNA
viruses. Four CoVs commonly circulate among humans: HCoV2-229E,-HKU1,-NL63 and …

Coronaviruses—drug discovery and therapeutic options

A Zumla, JFW Chan, EI Azhar, DSC Hui… - Nature reviews Drug …, 2016 - nature.com
In humans, infections with the human coronavirus (HCoV) strains HCoV-229E, HCoV-OC43,
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …

The molecular virology of coronaviruses

E Hartenian, D Nandakumar, A Lari, M Ly… - Journal of Biological …, 2020 - jbc.org
Few human pathogens have been the focus of as much concentrated worldwide attention as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19. Its …

The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle

S Ricciardi, AM Guarino, L Giaquinto, EV Polishchuk… - Nature, 2022 - nature.com
Abstract SARS-CoV-2, like other coronaviruses, builds a membrane-bound replication
organelle to enable RNA replication. The SARS-CoV-2 replication organelle is composed of …

[HTML][HTML] A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis

EJ Snijder, RWAL Limpens, AH de Wilde… - PLoS …, 2020 - journals.plos.org
Zoonotic coronavirus (CoV) infections, such as those responsible for the current severe
acute respiratory syndrome-CoV 2 (SARS-CoV-2) pandemic, cause grave international …

Emergence of a novel coronavirus, severe acute respiratory syndrome coronavirus 2: biology and therapeutic options

S Khan, R Siddique, MA Shereen, A Ali… - Journal of clinical …, 2020 - journals.asm.org
The new decade of the 21st century (2020) started with the emergence of a novel
coronavirus known as SARS-CoV-2 that caused an epidemic of coronavirus disease …

Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease

JFW Chan, SKP Lau, KKW To… - Clinical microbiology …, 2015 - journals.asm.org
The source of the severe acute respiratory syndrome (SARS) epidemic was traced to wildlife
market civets and ultimately to bats. Subsequent hunting for novel coronaviruses (CoVs) led …

[HTML][HTML] Double-membrane vesicles as platforms for viral replication

G Wolff, CE Melia, EJ Snijder, M Bárcena - Trends in microbiology, 2020 - cell.com
Viruses, as obligate intracellular parasites, exploit cellular pathways and resources in a
variety of fascinating ways. A striking example of this is the remodelling of intracellular …