The significant role of microRNAs in gliomas angiogenesis: a particular focus on molecular mechanisms and opportunities for clinical application

A Mafi, R Mannani, S Khalilollah, N Hedayati… - Cellular and Molecular …, 2023‏ - Springer
MicroRNAs (miRNAs) are non-coding RNAs with only 20–22 nucleic acids that inhibit gene
transcription and translation by binding to mRNA. MiRNAs have a diverse set of target genes …

[HTML][HTML] Nanomedicine: Technologies and Applications

M Farrokhi, F Taheri, M Farrokhi, YEK Tosi… - Kindle, 2024‏ - preferpub.org
Nanomedicine is an innovative field that merges nanotechnology with medicine, aiming to
enhance diagnosis, treatment, and prevention of diseases at the molecular level. This …

Lipid engineered nanomaterials: A novel paradigm shift for combating stroke

E Amulya, D Bahuguna, M Negi, V Phatale… - Applied Materials …, 2024‏ - Elsevier
Every year> 15 million individuals globally affect with a stroke and is considered the second
leading cause of mortality among all neurological disorders. Though numerous …

Nucleic acid-based therapeutics for the treatment of central nervous system disorders

R McCartan, O Khorkova, CH Volmar… - Frontiers in …, 2023‏ - frontiersin.org
Nucleic acid-based therapeutics (NBTs) are an emerging class of drugs with potential for the
treatment of a wide range of central nervous system conditions. To date, pertaining to CNS …

The battle of lipid-based nanocarriers against blood-brain barrier: A critical review

KK Abla, MM Mehanna - Journal of Drug Targeting, 2023‏ - Taylor & Francis
Central nervous system integrity is the state of brain functioning across sensory, cognitive,
emotional-social behaviors, and motor domains, allowing a person to realise his full …

[HTML][HTML] Advances in nucleic acid research: exploring the potential of oligonucleotides for therapeutic applications and biological studies

M Moccia, B Pascucci, M Saviano, MT Cerasa… - International Journal of …, 2023‏ - mdpi.com
In recent years, nucleic acids have emerged as powerful biomaterials, revolutionizing the
field of biomedicine. This review explores the multifaceted applications of nucleic acids …

Implantable Intraocular Fluorescence Sensor for Visualized Monitoring of Alzheimer's Disease

J Lim, H Lee, J Kim, CE Moon, JK Lee… - Advanced Functional …, 2025‏ - Wiley Online Library
With an increase in the older individuals, the global incidence of Alzheimer's disease (AD) is
increasing. Early diagnosis of AD necessitates long‐term monitoring; however, conventional …

Surface engineered nano architectonics: An evolving paradigm for tackling Alzheimer's disease

M Negi, E Amulya, V Phatale, N Abraham, A Hedaoo… - Life Sciences, 2024‏ - Elsevier
Abstract As per the World Health Organization (WHO) estimation, Alzheimer's disease (AD)
will affect 100 million population across the globe by 2050. AD is an incurable …

Aromatic Chinese medicine-decorated mesoporous nanoenzyme overcomes multiple biological barriers for solid tumor treatment

X Quan, B Hu, Y Li, I Zare, F Cheng, H Huang… - Chemical Engineering …, 2025‏ - Elsevier
The innate protective barriers of the organism and the dense extracellular matrix (ECM) in
solid tumor tissues, pose a significant challenge for effective drug transportation and …

Deciphering the role of nanocarrier-based nucleic acid delivery to the brain for the management of neurodegenerative disorders

S Panigrahy, A Sikder, E Amulya, S Shah… - Journal of Drug Delivery …, 2024‏ - Elsevier
Neurodegenerative diseases, such as Alzheimer's (AD) and Parkinson's (PD), are
characterized by the degeneration and eventual death of neurons in the central nervous …