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[HTML][HTML] Matrix vesicle-mediated mineralization and osteocytic regulation of bone mineralization
T Hasegawa, H Hongo, T Yamamoto, M Abe… - International journal of …, 2022 - mdpi.com
Bone mineralization entails two mineralization phases: primary and secondary
mineralization. Primary mineralization is achieved when matrix vesicles are secreted by …
mineralization. Primary mineralization is achieved when matrix vesicles are secreted by …
Consensus recommendations for the diagnosis and management of X-linked hypophosphatemia in Belgium
MR Laurent, J De Schepper, D Trouet… - Frontiers in …, 2021 - frontiersin.org
X-linked hypophosphatemia (XLH) is the most common genetic form of hypophosphatemic
rickets and osteomalacia. In this disease, mutations in the PHEX gene lead to elevated …
rickets and osteomalacia. In this disease, mutations in the PHEX gene lead to elevated …
Mineral tessellation in mouse enthesis fibrocartilage, Achilles tendon, and Hyp calcifying enthesopathy: A shared 3D mineralization pattern
The hallmark of enthesis architecture is the 3D compositional and structural gradient
encompassing four tissue zones–tendon/ligament, uncalcified fibrocartilage, calcified …
encompassing four tissue zones–tendon/ligament, uncalcified fibrocartilage, calcified …
Osteocytes and the pathogenesis of hypophosphatemic rickets
M Yamazaki, T Michigami - Frontiers in Endocrinology, 2022 - frontiersin.org
Since phosphorus is a component of hydroxyapatite, its prolonged deprivation affects bone
mineralization. Fibroblast growth factor 23 (FGF23) is essential for maintaining phosphate …
mineralization. Fibroblast growth factor 23 (FGF23) is essential for maintaining phosphate …
Dentoalveolar alterations in an adenine‐induced chronic kidney disease mouse model
Chronic kidney disease (CKD) is characterized by kidney damage and loss of renal function.
CKD mineral and bone disorder (CKD–MBD) describes the dysregulation of mineral …
CKD mineral and bone disorder (CKD–MBD) describes the dysregulation of mineral …
Opportunities for biomineralization research using multiscale computed X-ray tomography as exemplified by bone imaging
Biominerals typically have complex hierarchical structures traversing many length scales.
This makes their structural characterization complicated, since it requires 3D techniques that …
This makes their structural characterization complicated, since it requires 3D techniques that …
Bone hierarchical structure: spatial variation across length scales
Bone is a complex hierarchical biomineralized material, which is special amongst
biominerals because it is replete with cells, namely, osteocytes. While bone has been …
biominerals because it is replete with cells, namely, osteocytes. While bone has been …
Sclerostin antibody improves alveolar bone quality in the Hyp mouse model of X-linked hypophosphatemia (XLH)
KA Carpenter, DO Alkhatib, BA Dulion… - International Journal of …, 2023 - nature.com
X-linked hypophosphatemia (XLH) is a rare disease of elevated fibroblast growth factor 23
(FGF23) production that leads to hypophosphatemia and impaired mineralization of bone …
(FGF23) production that leads to hypophosphatemia and impaired mineralization of bone …