[HTML][HTML] The AGE Reader: A non-invasive method to assess long-term tissue damage

IM Atzeni, SC van de Zande, J Westra, J Zwerver… - Methods, 2022 - Elsevier
Abstract Aims Advanced glycation endproducts (AGEs) are sugar-modified adducts which
arise during non-enzymatic glycoxidative stress. These compounds may become …

Skin autofluorescence, a non-invasive marker of advanced glycation end products: clinical relevance and limitations

C Da Moura Semedo, MB Webb… - Postgraduate …, 2017 - academic.oup.com
Advanced glycation end products (AGEs) are protein-bound compounds derived from
glycaemic and oxidative stress that contain fluorescent properties, which can be non …

Musculoskeletal complications in type 1 diabetes

ME Larkin, A Barnie, BH Braffett, PA Cleary… - Diabetes …, 2014 - diabetesjournals.org
OBJECTIVE The development of periarticular thickening of skin on the hands and limited
joint mobility (cheiroarthropathy) is associated with diabetes and can lead to significant …

The diabetes control and complications trial/epidemiology of diabetes interventions and complications study at 30 years: summary and future directions

RA Gubitosi-Klug… - Diabetes care, 2014 - diabetesjournals.org
OBJECTIVE The Diabetes Control and Complications Trial/Epidemiology of Diabetes
Interventions and Complications (DCCT/EDIC) study continues to address knowledge gaps …

Understanding metabolic memory: a tale of two studies

RG Miller, TJ Orchard - Diabetes, 2020 - diabetesjournals.org
The results of the Diabetes Control and Complications Trial (DCCT) have given rise to much
encouragement in the battle to stave off the complications of type 1 diabetes, showing …

Skin fluorescence as a clinical tool for non-invasive assessment of advanced glycation and long-term complications of diabetes

BT Fokkens, AJ Smit - Glycoconjugate journal, 2016 - Springer
Glycation is important in the development of complications of diabetes mellitus and may
have a central role in the well-described glycaemic memory effect in develo** these …

Diabetes risk factors and bone microarchitecture as assessed by high-resolution peripheral quantitative computed tomography in adults with long-standing type 1 …

N Sinha Gregory, AJ Burghardt, JYC Backlund… - Diabetes …, 2024 - diabetesjournals.org
OBJECTIVE To determine whether type 1 diabetes and its complications are associated with
bone geometry and microarchitecture. RESEARCH DESIGN AND METHODS This cross …

Biochemical markers of bone turnover in older adults with type 1 diabetes

MR Rubin, IH De Boer, JYC Backlund… - The Journal of …, 2022 - academic.oup.com
Abstract Context Type 1 diabetes (T1D) is characterized by high fracture risk, yet little is
known regarding diabetes-related mechanisms or risk factors. Objective Determine whether …

Methods to investigate advanced glycation end-product and their application in clinical practice

D Corica, G Pepe, M Currò, T Aversa, A Tropeano… - Methods, 2022 - Elsevier
Advanced glycation end-products (AGEs) are heterogeneous compounds of irreversible
adducts principally derived from nonenzymatic glycation and glycoxidation of proteins. An …

The association of skin intrinsic fluorescence with type 1 diabetes complications in the DCCT/EDIC study

TJ Orchard, TJ Lyons, PA Cleary, BH Braffett… - Diabetes …, 2013 - diabetesjournals.org
OBJECTIVE To determine whether skin intrinsic fluorescence (SIF) is associated with long-
term complications of type 1 diabetes (T1D) and, if so, whether it is independent of chronic …