Population Genetics and Microevolutionary Theory Explore the fundamentals of the
biological implications of population genetic theory In the newly revised Second Edition of …

Interferon lambda 4 gene (IFNL4) encodes IFN-λ4, a new member of the IFN-λ family with
antiviral activity. In humans IFNL4 open reading frame is truncated by a polymorphic frame …

Insertions and deletions (indels) are common molecular evolutionary events. However,
probabilistic models for indel evolution are under-developed due to their computational …

The influence of positive selection sweeps in human evolution is increasingly debated,
although our ability to detect them is hampered by inherent uncertainties in the timing of past …

Small insertions and deletions (INDELs;≤ 50 bp) are the most common type of variability
after single nucleotide polymorphism (SNP). However, compared with SNPs, we know little …

The molecular clock hypothesis, which states that substitutions accumulate in protein
sequences at a constant rate, plays a fundamental role in molecular evolution but it is …

Fragmented populations of the endemic Italian hare (Lepus corsicanus) survive at low
density in central and southern Italy, in Sicily and Corsica, where the species was introduced …

Background Small insertions and deletions occur in humans at a lower rate compared to
nucleotide changes, but evolve under more constraint than nucleotide changes. While the …

Insertions and deletions (INDELs) remain understudied, despite being the most common
form of genetic variation after single nucleotide polymorphisms. This stems partly from the …

Background The variation rate in genomic regions associated with different alleles, impacts
to distinct evolutionary patterns involving rare alleles. The rare alleles bias towards genome …