[HTML][HTML] True-to-scale DNA-density maps correlate with major accessibility differences between active and inactive chromatin
M Gelléri, SY Chen, B Hübner, J Neumann, O Kröger… - Cell Reports, 2023 - cell.com
Chromatin compaction differences may have a strong impact on accessibility of individual
macromolecules and macromolecular assemblies to their DNA target sites. Estimates based …
macromolecules and macromolecular assemblies to their DNA target sites. Estimates based …
Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology
R Godschalk, C Faulk, J LaRocca… - Environmental and …, 2024 - Wiley Online Library
Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations.
However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic …
However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic …
Upregulation of the Oct3/4 network in basal breast cancer is associated with its metastatic potential and shows tissue dependent variability
RG Rajan, RI Krutilina, TN Ignatova… - International journal of …, 2023 - mdpi.com
Adaptive plasticity of Breast Cancer stem cells (BCSCs) is strongly correlated with cancer
progression and resistance, leading to a poor prognosis. In this study, we report the …
progression and resistance, leading to a poor prognosis. In this study, we report the …
Epigenetic Inheritance
M Fallet - Epigenetics in Biological Communication, 2024 - Springer
The field of epigenetics, orchestrating molecular communication at the genome-phenotype
interface, has gained significant importance over the last decades. Mitotic inheritance …
interface, has gained significant importance over the last decades. Mitotic inheritance …
Basic Epigenetic Mechanisms
JR Davie, H Sattarifard, SRN Sudhakar… - … Mechanisms in Health …, 2025 - Springer
The human genome consists of 23 chromosome pairs (22 autosomes and one pair of sex
chromosomes), with 46 chromosomes in a normal cell. In the interphase nucleus, the 2 m …
chromosomes), with 46 chromosomes in a normal cell. In the interphase nucleus, the 2 m …