Nasal drug delivery has been utilized for locally acting diseases for decades. The nose is
also a portal to the systemic circulation and central nervous system (CNS). In the age of …

In vitro–in vivo correlation (IVIVC) allows prediction of in vivo drug deposition from a nasally
inhaled drug based on in vitro drug measurements. In vitro measurements include physical …

The nasal cavity is the inlet to the human respiratory system and is responsible for the
olfactory sensation, filtering pollutant particulate matter, and humidifying the air. Many …

Although nasal inhalation products are becoming more and more important for the delivery
of medicines, characterization of these products for quality control and assessment of …

The objective of this study was to characterize the effects of multiple nasal prong interface
configurations on nasal depositional loss of pharmaceutical aerosols in a preterm infant …

Studies regarding the pollen transport and deposition in children nasal airways are still
scarce, especially the regional deposition doses, which is difficult to provide guidance for …

Abstract Dry Powder Inhalers (DPIs) are a mainstay in the treatment of obstructive
respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD) …

Objective To review the existing literature on the application of computational fluid dynamics
methods to study nasal particle deposition and to summarize and analyze the factors …

The COVID-19 pandemic has revealed significant disparities in disease severity and
mortality across various population groups and regions. These disparities cannot be …

Background: Understanding the morphology of nasal airways is important in determining the
nasal airway deposition of inhaled aerosol. Moreover, objective assessment of the anatomy …