Interleukin-10 (IL-10), first recognized for its ability to inhibit activation and effector function of
T cells, monocytes, and macrophages, is a multifunctional cytokine with diverse effects on …

Abstract Interleukin-10 (IL-10) is arguably the most potent anti-inflammatory cytokine. It is
produced by almost all the innate and adaptive immune cells. These cells also serve as its …

Defects in clearance of dying cells have been proposed to underlie the pathogenesis of
systemic lupus erythematosus (SLE). Mice lacking molecules associated with dying cell …

The exact patho-aetiology of systemic lupus erythematosus (SLE) remains elusive. An
extremely complicated and multifactorial interaction among various genetic and …

Flavonoids are natural polyphenolic compounds which are included in a panoply of drugs
and used to treat and/or manage human ailments such as metabolic, cardiovascular …

Objective To determine whether serum levels of B lymphocyte stimulator (BLyS) are
elevated in patients with systemic immune–based rheumatic diseases and correlate with …

Previous studies have indicated that the autoimmune phenomenon might be caused by an
imbalance of T helper cell (Th) cytokines. We measured the plasma concentrations of three …

Depression and anxiety cause severe loss of quality of life for patients with systemic lupus
erythematosus. The causes and factors that contribute to these psychological manifestations …

There is a great deal of interest in the identification of biomarkers that are closely associated
with disease activity in systemic lupus erythematosus (SLE), but few biomarkers have been …

B cells play critical roles in the pathogenesis of lupus. To examine the influence of B cells on
disease pathogenesis in a murine lupus model, New Zealand Black and New Zealand White …