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An Overview of Methods and Tools for Transfection of Eukaryotic Cells in vitro
A Fus-Kujawa, P Prus, K Bajdak-Rusinek… - … in bioengineering and …, 2021 - frontiersin.org
Transfection is a powerful analytical tool enabling studies of gene products and functions in
eukaryotic cells. Successful delivery of genetic material into cells depends on DNA quantity …
eukaryotic cells. Successful delivery of genetic material into cells depends on DNA quantity …
Understanding cell penetration of cyclic peptides
Approximately 75% of all disease-relevant human proteins, including those involved in
intracellular protein–protein interactions (PPIs), are undruggable with the current drug …
intracellular protein–protein interactions (PPIs), are undruggable with the current drug …
Overcoming the blood–brain barrier: the role of nanomaterials in treating neurological diseases
Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …
[HTML][HTML] Cell penetrating peptides: A concise review with emphasis on biomedical applications
Introduction The biological membranes as natural permeable barriers are required for
survival and function of living cells. However, these natural barriers could be a major …
survival and function of living cells. However, these natural barriers could be a major …
Overcoming endosomal entrapment in drug delivery
Intracellular delivery of biological agents such as peptides, proteins, and nucleic acids
generally rely on the endocytic pathway as the major uptake mechanism, resulting in their …
generally rely on the endocytic pathway as the major uptake mechanism, resulting in their …
Small bioactive peptides for biomaterials design and therapeutics
IW Hamley - Chemical reviews, 2017 - ACS Publications
This review is aimed to provide a concise yet extensive survey of key short bioactive peptide
sequences for a range of applications ranging from biomaterials development to peptides …
sequences for a range of applications ranging from biomaterials development to peptides …
Getting across the cell membrane: an overview for small molecules, peptides, and proteins
NJ Yang, MJ Hinner - Site-Specific Protein Labeling: Methods and …, 2014 - Springer
The ability to efficiently access cytosolic proteins is desired in both biological research and
medicine. However, targeting intracellular proteins is often challenging, because to reach …
medicine. However, targeting intracellular proteins is often challenging, because to reach …
How membrane-active peptides get into lipid membranes
Conspectus The structure–function relationship for a family of antimicrobial peptides (AMPs)
from the skin of Australian tree frogs is discussed and compared with that of peptide toxins …
from the skin of Australian tree frogs is discussed and compared with that of peptide toxins …
[HTML][HTML] Cell-penetrating peptides: 20 years later, where do we stand?
Twenty years ago, the discovery of peptides able to cross cellular membranes launched a
novel field in molecular delivery based on these non-invasive vectors, most commonly …
novel field in molecular delivery based on these non-invasive vectors, most commonly …
Anticancer activity of complexes of the third row transition metals, rhenium, osmium, and iridium
The clinical success of the platinum-based chemotherapeutic agents has prompted the
investigation of coordination and organometallic complexes of alternative metal centers for …
investigation of coordination and organometallic complexes of alternative metal centers for …