Background and purpose Preclinical studies indicate a normal tissue sparing effect using
ultra-high dose rate (FLASH) radiation with comparable tumor response. Most data so far …

Simple Summary Immunotherapy provides the unprecedented opportunity to prolong the
survival of cancer patients and even cure patients with previously untreatable malignancies …

Pediatric brain tumor treatments have a high success rate, but survivors are at risk of
cognitive sequelae that impact long-term quality of life. We summarize recent clinical and …

Simple Summary An increasing number of cancer patients are treated with proton therapy.
Nevertheless, there are still open questions that require preclinical studies, for example …

Combining radiation therapy with immunotherapy is a strategy to improve both treatments.
The purpose of this study was to compare responses for two syngeneic head and neck …

Purpose Ultra‐high dose rate FLASH irradiation (FLASH‐IR) has been shown to cause less
normal tissue damage compared with conventional irradiation (CONV‐IR), this is known as …

Background The purpose of this study was to investigate acute normal tissue responses in
the head and neck region following proton-or X-irradiation of a murine model. Materials and …

Charged particle radiotherapy, mainly using protons and carbon ions, provides physical
characteristics allowing for a volume conformal irradiation and a reduction of the integral …

Background Breast cancer is one of the most common cancer with high risk in females all
over the world. It is usually complicated with depression, which can further accelerate the …

Cytokines are mediators of inflammation that could lead to fibrosis. The aim was to monitor
cytokine levels in saliva and serum after locally fractionated radiotherapy of the head and …