Pigment epithelium-derived factor (PEDF) is a broadly expressed multifunctional member of
the serine proteinase inhibitor (serpin) family. This widely studied protein plays critical roles …

Pigment epithelium‐derived factor (PEDF) is a 50 kDa secreted glycoprotein that belongs to
the non‐inhibitory serpin family group. PEDF has been described as a natural angiogenesis …

Osteogenesis imperfecta (OI) is a heterogeneous genetic disorder characterized by bone
fragility and susceptibility to fractures after minimal trauma. After mutations in all known OI …

Systemic sclerosis (SSc) is a connective tissue disease of autoimmune origin characterized
by vascular dysfunction and extensive fibrosis of the skin and visceral organs. Vascular …

Vascular endothelial growth factor A (VEGFA) is involved in the pathogenesis of
vasoproliferative retinal diseases, such as exudative age-related macular degeneration …

Simple Summary While more efficient cancer treatments have led to a better quality of life
and to five-year survival rates of over 85% for localized tumors, these rates remain below …

The neuroprotective effects of small pigment epithelium-derived factor (PEDF) peptides
injected intravitreally as free peptides or delivered in poly (lactide-co-glycolide)(PLGA) …

Chronic inflammatory diseases, such as rheumatoid arthritis, spondyloarthritis, systemic
lupus erythematosus, Crohn's disease, periodontitis, and carcinoma metastasis frequently …

Mitigating oxidative stress-induced damage is critical to preserve neuronal function in
diseased or injured brains. This study explores the mechanisms contributing to the …

Pigment epithelium-derived factor (PEDF) is a potent antiangiogenic factor found in a wide
variety of tissues. Recent findings indicated that lack of PEDF leads to osteogenesis …