Integrin signaling
FG Giancotti, E Ruoslahti - science, 1999 - science.org
Cells reside in a protein network, the extracellular matrix (ECM), which they secrete and
mold into the intercellular space. The ECM exerts profound control over cells. The effects of …
mold into the intercellular space. The ECM exerts profound control over cells. The effects of …
Vascular smooth muscle cells and arterial stiffening: relevance in development, aging, and disease
P Lacolley, V Regnault, P Segers… - Physiological …, 2017 - journals.physiology.org
The cushioning function of large arteries encompasses distension during systole and recoil
during diastole which transforms pulsatile flow into a steady flow in the microcirculation …
during diastole which transforms pulsatile flow into a steady flow in the microcirculation …
Geometric control of cell life and death
Human and bovine capillary endothelial cells were switched from growth to apoptosis by
using micropatterned substrates that contained extracellular matrix-coated adhesive islands …
using micropatterned substrates that contained extracellular matrix-coated adhesive islands …
The role of myofibroblasts in physiological and pathological tissue repair
Myofibroblasts are the construction workers of wound healing and repair damaged tissues
by producing and organizing collagen/extracellular matrix (ECM) into scar tissue. Scar tissue …
by producing and organizing collagen/extracellular matrix (ECM) into scar tissue. Scar tissue …
Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry
AJ Maniotis, R Folberg, A Hess, EA Seftor… - The American journal of …, 1999 - Elsevier
Tissue sections from aggressive human intraocular (uveal) and metastatic cutaneous
melanomas generally lack evidence of significant necrosis and contain patterned networks …
melanomas generally lack evidence of significant necrosis and contain patterned networks …
Harnessing nanotopography and integrin–matrix interactions to influence stem cell fate
Stem cells respond to nanoscale surface features, with changes in cell growth and
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …
Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus
Research in cellular mechanotransduction often focuses on how extracellular physical
forces are converted into chemical signals at the cell surface. However, mechanical forces …
forces are converted into chemical signals at the cell surface. However, mechanical forces …
Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes
CP Brangwynne, TJ Mitchison… - Proceedings of the …, 2011 - National Acad Sciences
For most intracellular structures with larger than molecular dimensions, little is known about
the connection between underlying molecular activities and higher order organization such …
the connection between underlying molecular activities and higher order organization such …
Biomechanics and biophysics of cancer cells
S Suresh - Acta biomaterialia, 2007 - Elsevier
The past decade has seen substantial growth in research into how changes in the
biomechanical and biophysical properties of cells and subcellular structures influence, and …
biomechanical and biophysical properties of cells and subcellular structures influence, and …
Cellular mechanotransduction: putting all the pieces together again
DE Ingber - The FASEB journal, 2006 - Wiley Online Library
Analysis of cellular mechanotransduction, the mechanism by which cells convert mechanical
signals into biochemical responses, has focused on identification of critical …
signals into biochemical responses, has focused on identification of critical …