Cartilage-related collagens in osteoarthritis and rheumatoid arthritis: from pathogenesis to therapeutics

Z Ouyang, L Dong, F Yao, K Wang, Y Chen… - International Journal of …, 2023 - mdpi.com
Collagens serve essential mechanical functions throughout the body, particularly in the
connective tissues. In articular cartilage, collagens provide most of the biomechanical …

The role played by ferroptosis in osteoarthritis: evidence based on iron dyshomeostasis and lipid peroxidation

S Zhang, J Xu, H Si, Y Wu, S Zhou, B Shen - Antioxidants, 2022 - mdpi.com
Ferroptosis, a recently discovered regulated cell death modality, is characterised by iron-
dependent accumulation of lipid hydroperoxides, which can reach lethal levels but can be …

Causal factors for Osteoarthritis: a sco** review of mendelian randomization studies

E Alhassan, K Nguyen, MC Hochberg… - Arthritis Care & …, 2024 - Wiley Online Library
Objective Mendelian randomization (MR) has increasingly been utilized as a tool for
establishing causal relations between modifiable exposures and osteoarthritis (OA). The …

In vitro and in vivo investigations on arsenic-induced cartilage degeneration in osteoarthritis

GGD Suminda, Y Min, MW Ha, M Ghosh, DS Lee… - Journal of Hazardous …, 2024 - Elsevier
Heavy metals found in the environment, including arsenic (As) pose significant risks to
human health and present a risk factor for osteoarthritis (OA). This study researched the …

The Effect of Circulating Zinc, Selenium, Copper and Vitamin K1 on COVID-19 Outcomes: A Mendelian Randomization Study

MK Sobczyk, TR Gaunt - Nutrients, 2022 - mdpi.com
Abstract Background & Aims: Previous results from observational, interventional studies and
in vitro experiments suggest that certain micronutrients possess anti-viral and …

Development and validation of cuproptosis-related genes in synovitis during osteoarthritis progress

B Chang, Z Hu, L Chen, Z **, Y Yang - Frontiers in Immunology, 2023 - frontiersin.org
Osteoarthritis (OA) is one of the most common refractory degenerative joint diseases
worldwide. Synovitis is believed to drive joint cartilage destruction during OA pathogenesis …

The association of trace elements with arthritis in US adults: NHANES 2013–2016

T Guan, Z Wu, C Xu, G Su - Journal of Trace Elements in Medicine and …, 2023 - Elsevier
Background Arthritis is a common chronic disease, and is a major cause of disability and
chronic pain in adults. Considering inflammatory responses is closely related with trace …

Mechanisms of chondrocyte cell death in osteoarthritis: implications for disease progression and treatment

M Guan, Q Yu, G Zhou, Y Wang, J Yu, W Yang… - Journal of Orthopaedic …, 2024 - Springer
Osteoarthritis (OA) is a chronic joint disease characterized by the degeneration, destruction,
and excessive ossification of articular cartilage. The prevalence of OA is rising annually …

Circulating Copper Is Associated with Inflammatory Biomarkers in Greek Older Adults with Osteoarthritis

C Amerikanou, E Valsamidou, S Karavoltsos… - … Trace Element Research, 2024 - Springer
Osteoarthritis (OA) is the most common form of arthritis, that causes a significant decrease in
the quality of life of the afflicted and constitutes a great burden for the socioeconomic system …

Copper (II) complexes with carnosine conjugates of hyaluronic acids at different dipeptide loading percentages behave as multiple SOD mimics and stimulate Nrf2 …

F Bellia, V Lanza, I Naletova, B Tomasello… - Antioxidants, 2023 - mdpi.com
A series of copper (II) complexes with the formula [Cu2+ Hy (x) Car%] varying the molecular
weight (MW) of Hyaluronic acid (Hy, x= 200 or 700 kDa) conjugated with carnosine (Car) …