Lung cancer is the primary cause of mortality in the United States and around the globe.
Therapeutic options for lung cancer treatment include surgery, radiation therapy …

Small cell lung cancer (SCLC) is an aggressive form of lung cancer characterized by dismal
prognosis. Although SCLC may initially respond well to platinum-based chemotherapy, it …

PURPOSE In extensive-disease small-cell lung cancer (ED-SCLC), response rates to first-
line platinum-based chemotherapy are robust, but responses lack durability. CheckMate …

Pancreatic cancer is a major cause of cancer-related death, but despondently, the outlook
and prognosis for this resistant type of tumor have remained grim for a long time. Currently, it …

Purpose Patients with extensive-stage disease small-cell lung cancer (SCLC) have poor
survival outcomes despite first-line chemotherapy with etoposide and platinum. This …

Accumulating evidence indicates that CD8+ T cells in the tumor microenvironment and
systemic CD4+ T-cell immunity play an important role in mediating durable antitumor …

Simple Summary Small cell lung carcinoma (SCLC), is a high-grade neuroendocrine
carcinoma defined by its aggressiveness, poor differentiation, and somber prognosis. This …

Abstract T helper 17 (TH17) cells have well-described roles in autoimmune disease. Recent
evidence suggests that this effector T cell subset is also involved in tumour immunology and …

Simple Summary While most cancer immunotherapies have focused on CD8+ T cells as the
main drivers of antitumor immunity, increasing evidence indicates that CD4+ T cells also …

Small cell lung cancer (SCLC) is an aggressive neuroendocrine malignancy with a unique
natural history characterized by a short doubling time, high growth fraction, and early …