Skeletal and extraskeletal actions of vitamin D: current evidence and outstanding questions

R Bouillon, C Marcocci, G Carmeliet, D Bikle… - Endocrine …, 2019 - academic.oup.com
The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …

Vitamin D and cardiovascular disease prevention

S Pilz, N Verheyen, MR Grübler, A Tomaschitz… - Nature Reviews …, 2016 - nature.com
Vitamin D is a precursor of the steroid hormone calcitriol that is crucial for bone and mineral
metabolism. Both the high prevalence of vitamin D deficiency in the general population and …

Vitamin D and cardiovascular disease

PE Norman, JT Powell - Circulation research, 2014 - Am Heart Assoc
Vitamin D plays a classical hormonal role in skeletal health by regulating calcium and
phosphorus metabolism. Vitamin D metabolites also have physiological functions in …

Assessment of vitamin D status–a changing landscape

M Herrmann, CJL Farrell, I Pusceddu… - Clinical Chemistry and …, 2017 - degruyter.com
In recent years it has been shown that vitamin D deficiency is associated with an increased
incidence as well as the progression of a broad range of diseases including osteoporosis …

Vitamin D deficiency and risk of cardiovascular diseases: a narrative review

B Kheiri, A Abdalla, M Osman, S Ahmed, M Hassan… - Clinical …, 2018 - Springer
Vitamin D, a fat-soluble prohormone, has wide-ranging roles in the regulation of many
physiological processes through their interactions with the vitamin D receptors (VDR). It …

Links between vitamin D deficiency and cardiovascular diseases

I Mozos, O Marginean - BioMed research international, 2015 - Wiley Online Library
The aim of the present paper was to review the most important mechanisms explaining the
possible association of vitamin D deficiency and cardiovascular diseases, focusing on …

[HTML][HTML] Serum 25-hydroxyvitamin D and the risk of cardiovascular disease: dose-response meta-analysis of prospective studies

R Zhang, B Li, X Gao, R Tian, Y Pan, Y Jiang… - The American journal of …, 2017 - Elsevier
Background: During the past decade, an increasing number of prospective studies have
focused on the association between vitamin D and cardiovascular disease (CVD). However …

Vitamin D, Calcium Supplements, and Implications for Cardiovascular Health: JACC Focus Seminar

ED Michos, M Cainzos-Achirica, AS Heravi… - Journal of the American …, 2021 - jacc.org
Vitamin D and calcium supplements are commonly used, often together, to optimize bone
health. Multiple observational studies have linked low serum 25-hydroxyvitamin D …

Causes of type 2 diabetes in China

RCW Ma, X Lin, W Jia - The Lancet Diabetes & Endocrinology, 2014 - thelancet.com
The prevalence of diabetes in China has increased substantially over recent decades, with
more than 100 million people estimated to be affected by the disease presently. During this …

Vitamin D deficiency is independently associated with the extent of coronary artery disease

M Verdoia, A Schaffer, C Sartori… - European journal of …, 2014 - Wiley Online Library
Abstract Background Vitamin D (25‐OH D3) deficiency represents a rising social and
economic problem in Western countries. Vitamin D has been recently reported to modulate …