Calcium carbonate (CaCO3) is an important inorganic mineral in biological and geological
systems. Traditionally, it is widely used in plastics, papermaking, ink, building materials …

Successful materials design for bone-tissue engineering requires an understanding of the
composition and structure of native bone tissue, as well as appropriate selection of …

Polyphenols are a class of ubiquitous compounds distributed in nature, with fascinating
inherent biocompatible, bioadhesive, antioxidant, and antibacterial properties. The unique …

Successful regeneration of large segmental bone defects remains a major challenge in
clinical orthopedics, thus it is of important significance to fabricate a suitable alternative …

Electrospinning provides a versatile technique for the preparation of matrices with
micro/nanoscopic fibers. The non-woven polymer materials produced by electrospinning …

Collagen, an abundant extracellular matrix protein, has been found to have a lot of
pharmaceuticals, medicine, food, and cosmetics applications. Increased knowledge of …

Natural bone is a mineralized biological material, which serves a supportive and protective
framework for the body, stores minerals for metabolism, and produces blood cells nourishing …

This review is intended to give a state of the art description of scaffold-based strategies
utilized in Bone Tissue Engineering. Numerous scaffolds have been tested in the orthopedic …

Surface interaction at the biomaterial–cell interface is essential for a variety of cellular
functions, such as adhesion, proliferation, and differentiation. Nevertheless, changes in the …

Collagen type I is the main organic constituent of the bone extracellular matrix and has been
used for decades as scaffolding material in bone tissue engineering approaches when …