Ultrahigh–dose rate FLASH radiotherapy (FLASH-RT) is a potentially paradigm-shifting
treatment modality that holds the promise of expanding the therapeutic index for nearly any …

Cardiovascular diseases (CVDs) have been the prime cause of mortality worldwide for
decades. However, the underlying mechanism of their pathogenesis is not fully clear yet. It …

NADPH oxidases of the Nox family are important enzymatic sources of reactive oxygen
species (ROS). Numerous homologue-specific mechanisms control the activity of this …

A large body of literature suggest that vascular reduced nicotinamide-adenine dinucleotide
phosphate (NADPH) oxidases are important sources of reactive oxygen species. Many …

Stroke is an emerging major health problem often resulting in death or disability.
Hyperlipidemia, high blood pressure and diabetes are well established risk factors …

Sleep-disordered breathing and obstructive sleep apnea (OSA) are highly prevalent
disorders throughout the lifespan, which may affect up to 2–10% of the population, and have …

The endothelium is essential for the maintenance of vascular homeostasis. Central to this
role is the production of endothelium-derived nitric oxide (EDNO), synthesized by the …

This study aimed to promote red pitaya fruit parts as alternate sources of nutraceuticals. The
red pitaya of Chinese origin was determined for its in vitro efficacy, where the fruit extracts …

Oxidative stress is known to be associated with many pathologies including inflammation,
cancer, diabetes, etc. However, oxidative stress resulting from the imbalance between …

BACKGROUND AND PURPOSE NO produced by endothelial NOS is needed for normal
vascular function. During diabetes, aging and hypertension, elevated levels of arginase can …