Oxidative stress impairs function and increases redox protein modifications in human spermatozoa

T Morielli, C O'Flaherty - Reproduction, 2015 - rep.bioscientifica.com
Oxidative stress, generated by excessive reactive oxygen species (ROS) or decreased
antioxidant defenses (and possibly both), is associated with male infertility. Oxidative stress …

The national animal germplasm program: challenges and opportunities for poultry genetic resources

HD Blackburn - Poultry science, 2006 - Elsevier
Abstract In the United States, poultry genetic resources have consolidated because of
economic pressures. Such consolidations can potentially jeopardize the poultry industry and …

piggyBac transposition into primordial germ cells is an efficient tool for transgenesis in chickens

TS Park, JY Han - Proceedings of the National Academy of …, 2012 - National Acad Sciences
Transgenic birds embody one of the most potent and exciting research tools in
biotechnology for agriculture, medicine, and model animals. To date, retrovirus-or lentivirus …

Basic fibroblast growth factor activates MEK/ERK cell signaling pathway and stimulates the proliferation of chicken primordial germ cells

JW Choi, S Kim, TM Kim, YM Kim, HW Seo, TS Park… - PloS one, 2010 - journals.plos.org
Background Long-term maintenance of avian primordial germ cells (PGCs) in vitro has
tremendous potential because it can be used to deepen our understanding of the biology of …

Germ cells and transgenesis in chickens

JY Han - Comparative immunology, microbiology and infectious …, 2009 - Elsevier
Chickens have proven to be useful organisms for transgenic research. This work provides
enormous benefits in advancing animal biotechnology and aids in the development of …

Current approaches and applications in avian genome editing

J Lee, DH Kim, K Lee - International Journal of Molecular Sciences, 2020 - mdpi.com
Advances in genome-editing technologies and sequencing of animal genomes enable
researchers to generate genome-edited (GE) livestock as valuable animal models that …

Development, differentiation and manipulation of chicken germ cells

Y Nakamura, H Kagami… - Development, growth & …, 2013 - Wiley Online Library
Germ cells are the only cell type capable of transmitting genetic information to the next
generation. During development, they are set aside from all somatic cells of the embryo. In …

Genetic regulation of avian testis development

MA Estermann, AT Major, CA Smith - Genes, 2021 - mdpi.com
As in other vertebrates, avian testes are the site of spermatogenesis and androgen
production. The paired testes of birds differentiate during embryogenesis, first marked by the …

Development of novel markers for the characterization of chicken primordial germ cells

JG Jung, DK Kim, TS Park, SD Lee, JM Lim… - Stem Cells, 2005 - academic.oup.com
This study was undertaken to develop novel markers for chicken primordial germ cells
(PGCs), which are of potentially enormous value in transgenic research. Gonadal cells …

Poultry genetic resource conservation using primordial germ cells

Y Nakamura - Journal of Reproduction and Development, 2016 - jstage.jst.go.jp
The majority of poultry genetic resources are maintained in situ in living populations.
However, in situ conservation of poultry genetic resources always carries the risk of loss …