Peptidic foldamers: ram** up diversity

TA Martinek, F Fülöp - Chemical Society Reviews, 2012 - pubs.rsc.org
Non-natural folded polymers (foldamers) display considerable versatility, and the design of
such molecules is of great current interest. In this respect, peptidic foldamers are perhaps …

Peptidomimetics via modifications of amino acids and peptide bonds

I Avan, CD Hall, AR Katritzky - Chemical Society Reviews, 2014 - pubs.rsc.org
Peptidomimetics represent an important field in chemistry, pharmacology and material
science as they circumvent the limitations of traditional peptides used in therapy. Self …

Diversifying the structural architecture of synthetic oligomers: the hetero foldamer approach

A Roy, P Prabhakaran, PK Baruah… - Chemical …, 2011 - pubs.rsc.org
Conformationally ordered synthetic oligomers, also called “foldamers”, have attracted
considerable attention in recent years owing to their ability to mimic the structural …

Investigation of 20S-hydroxyvitamin D3 analogs and their 1α-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities

Z Lin, SR Marepally, ESY Goh, CYS Cheng… - Scientific reports, 2018 - nature.com
Abstract 20 S-hydroxyvitamin D3 [20 S (OH) D3] is anti-inflammatory and not hypercalcemic,
suggesting its potential as a lead compound. In this study, side chain modified 20 S (OH) D3 …

N–O linkage in carbohydrates and glycoconjugates

N Chen, J **e - Organic & Biomolecular Chemistry, 2016 - pubs.rsc.org
The importance of oligosaccharides and their conjugates in various biological and
pathological processes has stimulated growing interest in the development of (neo) …

Aminooxylated carbohydrates: Synthesis and applications

C Pifferi, GC Daskhan, M Fiore, TC Shiao… - Chemical …, 2017 - ACS Publications
Among other classes of biomolecules, carbohydrates and glycoconjugates are widely
involved in numerous biological functions. In addition to addressing the related synthetic …

Ab initio MO Theory – An Important Tool in Foldamer Research: Prediction of Helices in Oligomers of ω‐Amino Acids

C Baldauf, HJ Hofmann - Helvetica Chimica Acta, 2012 - Wiley Online Library
The enormous developments of computer technologies allow the broad employment of ab
initio MO theory in foldamer research. In this review, we demonstrate the efficiency and …

Tetrahydrofuran amino acids of the past decade

V Rjabovs, M Turks - Tetrahedron, 2013 - Elsevier
Chemists have long sought chemical substances that can substitute for or mimic natural
molecules or building blocks. These mimics would enable easier syntheses and thus …

Synthesis and Structural Characterization of Homochiral Homo‐oligomers of Parent cis‐ and trans‐Furanoid‐β‐Amino Acids

SK Pandey, GF Jogdand, JCA Oliveira… - … A European Journal, 2011 - Wiley Online Library
The synthesis of homochiral homo‐oligomers of cis‐and trans‐3‐aminotetrahydrofuran‐2‐
carboxylic acids (parent cis‐and trans‐furanoid‐β‐amino acids, referred to as “cis‐/trans …

Efficient preparation of aminoxyacyl amides, aminoxy hybrid peptides, and α-aminoxy peptides

AR Katritzky, I Avan, SR Tala - The Journal of Organic Chemistry, 2009 - ACS Publications
N-(Pg-α-aminoxy acids) 1a− g are converted to N-(Pg-α-aminoxyacyl) benzotriazoles 2a− g,
which react under mild conditions with amines, α-amino acids/α-dipeptides, and α-aminoxy …