Microenvironmental host–microbe interactions in chronic inflammatory skin diseases

L Bay, GB Jemec, HC Ring - Apmis, 2024 - Wiley Online Library
Several microbiome studies have recently demonstrated microbial dysbiosis in various
chronic inflammatory skin diseases, and it is considered an important role in the …

Neutrophils in Atopic Dermatitis

CC Chiang, WJ Cheng, JRMS Dela Cruz… - Clinical Reviews in …, 2024 - Springer
Neutrophils have a critical role in inflammation. Recent studies have identified their
distinctive presence in certain types of atopic dermatitis (AD), yet their exact function remains …

Crosstalk between keratinocytes and neutrophils shapes skin immunity against S. aureus infection

J Focken, B Schittek - Frontiers in Immunology, 2024 - frontiersin.org
Introduction Staphylococcus aureus (S. aureus) infection of the skin leads to a rapid initial
innate immune response with keratinocytes in the epidermis as the initial sensors …

Eosinophil extracellular vesicles and DNA traps in allergic inflammation

T Weihrauch, RCN Melo, N Gray, D Voehringer… - Frontiers in …, 2024 - frontiersin.org
Eosinophil granulocytes, a specialized subset of white blood cells, have traditionally been
associated with allergic responses and parasitic infections. However, recent research has …

Commensal microbe regulation of skin cells in disease

Y Gan, J Zhang, F Qi, Z Hu, E Sweren, SK Reddy… - Cell host & …, 2024 - cell.com
Human skin is the host to various commensal microbes that constitute a substantial
microbial community. The reciprocal communication between these microbial inhabitants …

[HTML][HTML] TcaR is an important transcriptional regulator involved in environmental stress response and virulence in foodborne Staphylococcus aureus

H Pei, X Lei, F Kong, S Chen, H Wang, J Guo, M Wang… - LWT, 2024 - Elsevier
Staphylococcus aureus is a pathogenic microorganism that widely exists in milk and dairy
products, posing a great challenge to food safety and human health. Although TcaR is …

Effects of Huang-Lian-Jie-Du decoction on improving skin barrier function and modulating T helper cell differentiation in 1-chloro-2, 4-dinitrobenzene-induced atopic …

H Zhang, Q Li, Y Li, J Guan, K Li, Y Chen - Frontiers in Pharmacology, 2024 - frontiersin.org
Background: Atopic dermatitis (AD) is among the most frequently encountered skin
diseases, bothering a considerable number of patients. Today, corticosteroids and …

[HTML][HTML] Neutrophil extracellular traps drive kidney stone formation

Z Yang, X Chen, G Qi, J Gu, Z Liu, X Zhang - Kidney Diseases, 2024 - karger.com
Introduction: This study aims to explore the contribution of neutrophil extracellular traps
(NETs) to kidney stones. Methods: The microarray data from GSE73680 and bioinformatic …

Lipase-mediated detoxification of host-derived antimicrobial fatty acids by Staphylococcus aureus

A Kengmo Tchoupa, AMA Elsherbini, J Camus… - Communications …, 2024 - nature.com
Long-chain fatty acids with antimicrobial properties are abundant on the skin and mucosal
surfaces, where they are essential to restrict the proliferation of opportunistic pathogens …

Atopic Dermatitis and IgE-Mediated Food Allergy: Common Biologic Targets for Therapy and Prevention

HM Kenney, J Battaglia, K Herman, LA Beck - Annals of Allergy, Asthma & …, 2024 - Elsevier
Objective: To highlight common mechanistic targets for the treatment of atopic dermatitis
(AD) and IgE-mediated food allergy (IgE-FA) with potential to be effective for both diseases …